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Ocimum sanctum Linn--a study on gastric ulceration and gastric secretion in rats.
Indian J Physiol Pharmacol. 1993 Jan; 37(1):91-2.IJ

Abstract

The antiulcerogenic property of Ocimum sanctum Linn (Tulsi) was studied in pyloric ligated and pyloric ligated & aspirin treated rats. The extract of OSL reduced the ulcer index, free & total acidity on acute and chronic administration. Seven days pretreatment with the drug increased the mucous secretion also. It may be concluded that OSL extract has antiulcerogenic property against experimental ulcers, and it is due to its ability to reduce acid secretion and increase mucous secretion.

Authors+Show Affiliations

Mandal S
Department of Pharmacology, Burdwan Medical College, West Bengal.
Das DN
No affiliation info available
De K
No affiliation info available
Ray K
No affiliation info available
Roy G
No affiliation info available
Chaudhuri SB
No affiliation info available
Sahana CC
No affiliation info available
Chowdhuri MK
No affiliation info available

MeSH

AnimalsAnti-Ulcer AgentsFemaleGastric JuiceGastric MucosaHydrogen-Ion ConcentrationIndiaMalePlant ExtractsPlants, MedicinalRatsRats, WistarStomach Ulcer

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

8449557

Citation

Mandal, S, et al. "Ocimum Sanctum Linn--a Study On Gastric Ulceration and Gastric Secretion in Rats." Indian Journal of Physiology and Pharmacology, vol. 37, no. 1, 1993, pp. 91-2.
Mandal S, Das DN, De K, et al. Ocimum sanctum Linn--a study on gastric ulceration and gastric secretion in rats. Indian J Physiol Pharmacol. 1993;37(1):91-2.
Mandal, S., Das, D. N., De, K., Ray, K., Roy, G., Chaudhuri, S. B., Sahana, C. C., & Chowdhuri, M. K. (1993). Ocimum sanctum Linn--a study on gastric ulceration and gastric secretion in rats. Indian Journal of Physiology and Pharmacology, 37(1), 91-2.
Mandal S, et al. Ocimum Sanctum Linn--a Study On Gastric Ulceration and Gastric Secretion in Rats. Indian J Physiol Pharmacol. 1993;37(1):91-2. PubMed PMID: 8449557.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Ocimum sanctum Linn--a study on gastric ulceration and gastric secretion in rats. AU - Mandal,S, AU - Das,D N, AU - De,K, AU - Ray,K, AU - Roy,G, AU - Chaudhuri,S B, AU - Sahana,C C, AU - Chowdhuri,M K, PY - 1993/1/1/pubmed PY - 1993/1/1/medline PY - 1993/1/1/entrez SP - 91 EP - 2 JF - Indian journal of physiology and pharmacology JO - Indian J Physiol Pharmacol VL - 37 IS - 1 N2 - The antiulcerogenic property of Ocimum sanctum Linn (Tulsi) was studied in pyloric ligated and pyloric ligated & aspirin treated rats. The extract of OSL reduced the ulcer index, free & total acidity on acute and chronic administration. Seven days pretreatment with the drug increased the mucous secretion also. It may be concluded that OSL extract has antiulcerogenic property against experimental ulcers, and it is due to its ability to reduce acid secretion and increase mucous secretion. SN - 0019-5499 UR - https://www.unboundmedicine.com/medline/citation/8449557/Ocimum_sanctum_Linn__a_study_on_gastric_ulceration_and_gastric_secretion_in_rats_ DB - PRIME DP - Unbound Medicine ER -