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Vasectomy and prostate cancer in US blacks and whites.
Am J Epidemiol 1993; 137(3):263-9AJ

Abstract

A large population-based case-control study was carried out to investigate the association between vasectomy and prostate cancer risk in black and in white men in the United States. Study subjects resided in the geographic areas covered by the population-based cancer registries of the Georgia Center for Cancer Statistics, or the Metropolitan Detroit Cancer Surveillance System, or in 10 counties included in the cancer registry of the New Jersey State Health Department. Cases for this study were men aged 40-79 years identified from pathology and outpatient records at hospitals covered by these registries, newly diagnosed with pathologically confirmed prostate cancer between August 1, 1986, and April 30, 1989. Population controls less than age 65 years were selected at periodic intervals by random digit dialing. Older controls were systematically selected (after a random start) from computerized records of the Health Care Finance Administration. A statistically nonsignificant excess risk (odds ratio (OR) = 1.6, 95% confidence interval (CI) 0.5-4.8) for prostate cancer associated with vasectomy was noted in blacks. Overall, the risk for prostate cancer associated with vasectomy in whites was not elevated (OR = 1.1, 95% CI 0.8-1.7). An increase in risk was found, however, for white men who had had a vasectomy 20 years or more prior to study (OR = 1.7, 95% CI 0.9-3.3) or who had had a vasectomy at less than age 35 years (OR = 2.2, 95% CI 1.0-4.4). For the total study group, the odds ratio associated with men who had a vasectomy 20 or more years prior to study was 1.5 (95% CI 0.8-2.7), and the odds ratio associated with men who had had a vasectomy at less than age 35 years was 2.0 (95% CI 1.0-4.0). Further detailed analysis showed that young age at vasectomy (less than age 35 years) was a more important risk factor than was years since vasectomy.

Authors+Show Affiliations

Environmental Epidemiology Branch, National Cancer Institute, Bethesda, MD 20892.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8452134

Citation

Hayes, R B., et al. "Vasectomy and Prostate Cancer in US Blacks and Whites." American Journal of Epidemiology, vol. 137, no. 3, 1993, pp. 263-9.
Hayes RB, Pottern LM, Greenberg R, et al. Vasectomy and prostate cancer in US blacks and whites. Am J Epidemiol. 1993;137(3):263-9.
Hayes, R. B., Pottern, L. M., Greenberg, R., Schoenberg, J., Swanson, G. M., Liff, J., ... Hoover, R. N. (1993). Vasectomy and prostate cancer in US blacks and whites. American Journal of Epidemiology, 137(3), pp. 263-9.
Hayes RB, et al. Vasectomy and Prostate Cancer in US Blacks and Whites. Am J Epidemiol. 1993 Feb 1;137(3):263-9. PubMed PMID: 8452134.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Vasectomy and prostate cancer in US blacks and whites. AU - Hayes,R B, AU - Pottern,L M, AU - Greenberg,R, AU - Schoenberg,J, AU - Swanson,G M, AU - Liff,J, AU - Schwartz,A G, AU - Brown,L M, AU - Hoover,R N, PY - 1993/2/1/pubmed PY - 1993/2/1/medline PY - 1993/2/1/entrez KW - Age Factors KW - Americas KW - Biology KW - Blacks KW - Cancer KW - Case Control Studies KW - Cultural Background KW - Demographic Factors KW - Developed Countries KW - Diseases KW - Ethnic Groups KW - Family Planning KW - Genitalia KW - Genitalia, Male KW - Male Sterilization KW - Neoplasms KW - North America KW - Northern America KW - Physiology KW - Population KW - Population Characteristics KW - Prostate KW - Research Methodology KW - Risk Factors KW - Sterilization, Sexual KW - Studies KW - United States KW - Urogenital System KW - Vasectomy KW - Whites SP - 263 EP - 9 JF - American journal of epidemiology JO - Am. J. Epidemiol. VL - 137 IS - 3 N2 - A large population-based case-control study was carried out to investigate the association between vasectomy and prostate cancer risk in black and in white men in the United States. Study subjects resided in the geographic areas covered by the population-based cancer registries of the Georgia Center for Cancer Statistics, or the Metropolitan Detroit Cancer Surveillance System, or in 10 counties included in the cancer registry of the New Jersey State Health Department. Cases for this study were men aged 40-79 years identified from pathology and outpatient records at hospitals covered by these registries, newly diagnosed with pathologically confirmed prostate cancer between August 1, 1986, and April 30, 1989. Population controls less than age 65 years were selected at periodic intervals by random digit dialing. Older controls were systematically selected (after a random start) from computerized records of the Health Care Finance Administration. A statistically nonsignificant excess risk (odds ratio (OR) = 1.6, 95% confidence interval (CI) 0.5-4.8) for prostate cancer associated with vasectomy was noted in blacks. Overall, the risk for prostate cancer associated with vasectomy in whites was not elevated (OR = 1.1, 95% CI 0.8-1.7). An increase in risk was found, however, for white men who had had a vasectomy 20 years or more prior to study (OR = 1.7, 95% CI 0.9-3.3) or who had had a vasectomy at less than age 35 years (OR = 2.2, 95% CI 1.0-4.4). For the total study group, the odds ratio associated with men who had a vasectomy 20 or more years prior to study was 1.5 (95% CI 0.8-2.7), and the odds ratio associated with men who had had a vasectomy at less than age 35 years was 2.0 (95% CI 1.0-4.0). Further detailed analysis showed that young age at vasectomy (less than age 35 years) was a more important risk factor than was years since vasectomy. SN - 0002-9262 UR - https://www.unboundmedicine.com/medline/citation/8452134/Vasectomy_and_prostate_cancer_in_US_blacks_and_whites_ L2 - https://academic.oup.com/aje/article-lookup/doi/10.1093/oxfordjournals.aje.a116673 DB - PRIME DP - Unbound Medicine ER -