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[Intravital microscopic and laser Doppler method estimates of cochlear blood flow--effect of transient ischemia on inner ear blood flow].
Nihon Jibiinkoka Gakkai Kaiho. 1993 Feb; 96(2):260-70.NJ

Abstract

Cochlear blood flow (CoBF) was measured by intravital microscopy (IVM) and laser Doppler (LD) methods in normal guinea pigs and after a single norepinephrine (NE) injection into the carotid artery. CoBF changed in proportion to BP changes in normal animals. CoBF values by LD correlated well (r = 0.67) with CoBF measured by IVM when BP changed in the 35 and 70 mm Hg range. A linear regression line was obtained as y = 1.407X-2.996. No correlation was found between the diameters of radiating arterioles (RA) and blood volume (i.e., the hemoglobin concentration index). NE injection into the carotid artery induced the formation of sludge at RA, resulting in decreased local CoBF. A decrement in CoBF was also observed by LD after injection. Although similar patterns of CoBF changes were obtained by these two methods after injection, the degree of CoBF change by LD appeared to be lower than that by IVM. Our result indicates that the combination of these two methods provides a better understanding of cochlear circulation.

Authors+Show Affiliations

Department of Otolaryngology, Itami Municipal Hospital, Hyogo.

Pub Type(s)

Comparative Study
English Abstract
Journal Article

Language

jpn

PubMed ID

8463889

Citation

Fuzisaki, Y. "[Intravital Microscopic and Laser Doppler Method Estimates of Cochlear Blood Flow--effect of Transient Ischemia On Inner Ear Blood Flow]." Nihon Jibiinkoka Gakkai Kaiho, vol. 96, no. 2, 1993, pp. 260-70.
Fuzisaki Y. [Intravital microscopic and laser Doppler method estimates of cochlear blood flow--effect of transient ischemia on inner ear blood flow]. Nihon Jibiinkoka Gakkai Kaiho. 1993;96(2):260-70.
Fuzisaki, Y. (1993). [Intravital microscopic and laser Doppler method estimates of cochlear blood flow--effect of transient ischemia on inner ear blood flow]. Nihon Jibiinkoka Gakkai Kaiho, 96(2), 260-70.
Fuzisaki Y. [Intravital Microscopic and Laser Doppler Method Estimates of Cochlear Blood Flow--effect of Transient Ischemia On Inner Ear Blood Flow]. Nihon Jibiinkoka Gakkai Kaiho. 1993;96(2):260-70. PubMed PMID: 8463889.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Intravital microscopic and laser Doppler method estimates of cochlear blood flow--effect of transient ischemia on inner ear blood flow]. A1 - Fuzisaki,Y, PY - 1993/2/1/pubmed PY - 1993/2/1/medline PY - 1993/2/1/entrez SP - 260 EP - 70 JF - Nihon Jibiinkoka Gakkai kaiho JO - Nihon Jibiinkoka Gakkai Kaiho VL - 96 IS - 2 N2 - Cochlear blood flow (CoBF) was measured by intravital microscopy (IVM) and laser Doppler (LD) methods in normal guinea pigs and after a single norepinephrine (NE) injection into the carotid artery. CoBF changed in proportion to BP changes in normal animals. CoBF values by LD correlated well (r = 0.67) with CoBF measured by IVM when BP changed in the 35 and 70 mm Hg range. A linear regression line was obtained as y = 1.407X-2.996. No correlation was found between the diameters of radiating arterioles (RA) and blood volume (i.e., the hemoglobin concentration index). NE injection into the carotid artery induced the formation of sludge at RA, resulting in decreased local CoBF. A decrement in CoBF was also observed by LD after injection. Although similar patterns of CoBF changes were obtained by these two methods after injection, the degree of CoBF change by LD appeared to be lower than that by IVM. Our result indicates that the combination of these two methods provides a better understanding of cochlear circulation. SN - 0030-6622 UR - https://www.unboundmedicine.com/medline/citation/8463889/[Intravital_microscopic_and_laser_Doppler_method_estimates_of_cochlear_blood_flow__effect_of_transient_ischemia_on_inner_ear_blood_flow]_ L2 - http://www.medicalonline.jp/meteo_linkout.php?issn=0030-6622&volume=96&issue=2&spage=260 DB - PRIME DP - Unbound Medicine ER -