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[Inhibition of compound 48--80 induced histamine liberation from mast cells by triton X-100].
Biull Eksp Biol Med. 1979 Feb; 87(2):185-7.BE

Abstract

Triton X-100 at concentrations preceding those which liberated histamine, produced dose-dependent inhibition of compound 48/80-induced histamine release from rat mast cells. Triton X-100 (0.00002 1/1) depleted ATP content in the mast cells and blocked compound 48/80-induced histamine release. The inhibition of compound 48/80-induced histamine release and depletion of the ATP content in the mast cells was reversed by glucose (10 mmole). It is concluded that inhibition by Triton X-100 of histamine release induced by compound 48/80 is dependent on inhibition of energy production.

Authors

Gushchin IS
No affiliation info available
Deriugin IL
No affiliation info available

MeSH

Adenosine TriphosphateAnimalsDose-Response Relationship, DrugHistamine ReleaseMaleMast CellsPolyethylene GlycolsRatsp-Methoxy-N-methylphenethylamine

Pub Type(s)

Journal Article

Language

rus

PubMed ID

84694

Citation

Gushchin, I S., and I L. Deriugin. "[Inhibition of Compound 48--80 Induced Histamine Liberation From Mast Cells By Triton X-100]." Biulleten' Eksperimental'noi Biologii I Meditsiny, vol. 87, no. 2, 1979, pp. 185-7.
Gushchin IS, Deriugin IL. [Inhibition of compound 48--80 induced histamine liberation from mast cells by triton X-100]. Biull Eksp Biol Med. 1979;87(2):185-7.
Gushchin, I. S., & Deriugin, I. L. (1979). [Inhibition of compound 48--80 induced histamine liberation from mast cells by triton X-100]. Biulleten' Eksperimental'noi Biologii I Meditsiny, 87(2), 185-7.
Gushchin IS, Deriugin IL. [Inhibition of Compound 48--80 Induced Histamine Liberation From Mast Cells By Triton X-100]. Biull Eksp Biol Med. 1979;87(2):185-7. PubMed PMID: 84694.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Inhibition of compound 48--80 induced histamine liberation from mast cells by triton X-100]. AU - Gushchin,I S, AU - Deriugin,I L, PY - 1979/2/1/pubmed PY - 1979/2/1/medline PY - 1979/2/1/entrez SP - 185 EP - 7 JF - Biulleten' eksperimental'noi biologii i meditsiny JO - Biull Eksp Biol Med VL - 87 IS - 2 N2 - Triton X-100 at concentrations preceding those which liberated histamine, produced dose-dependent inhibition of compound 48/80-induced histamine release from rat mast cells. Triton X-100 (0.00002 1/1) depleted ATP content in the mast cells and blocked compound 48/80-induced histamine release. The inhibition of compound 48/80-induced histamine release and depletion of the ATP content in the mast cells was reversed by glucose (10 mmole). It is concluded that inhibition by Triton X-100 of histamine release induced by compound 48/80 is dependent on inhibition of energy production. SN - 0365-9615 UR - https://www.unboundmedicine.com/medline/citation/84694/[Inhibition_of_compound_48__80_induced_histamine_liberation_from_mast_cells_by_triton_X_100]_ DB - PRIME DP - Unbound Medicine ER -