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Pylephlebitis associated with diverticulitis.
South Med J. 1993 May; 86(5):578-80.SM

Abstract

We have reported the cases of two patients who had acute pylephlebitis associated with portal vein thrombosis and septic hepatic emboli as a result of right colonic diverticulitis. Although rare, pylephlebitis is a treatable but often lethal complication of intra-abdominal sepsis. Several bacterial pathogens, especially Escherichia coli are associated with pylephlebitis. Early suspicion and prompt antibiotic therapy can lead to resolution of portal vein thrombosis and hepatic abscess formation, resulting in full recovery for the patient. Surgery may not be required. Our two patients received ampicillin--the best first-line drug--until specific antibiotic therapy could be given. Early administration of a broad spectrum antibiotic is essential.

Authors+Show Affiliations

Department of Surgery, Newton-Wellesley Hospital, Mass.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

8488411

Citation

Perez-Cruet, M J., et al. "Pylephlebitis Associated With Diverticulitis." Southern Medical Journal, vol. 86, no. 5, 1993, pp. 578-80.
Perez-Cruet MJ, Grable E, Drapkin MS, et al. Pylephlebitis associated with diverticulitis. South Med J. 1993;86(5):578-80.
Perez-Cruet, M. J., Grable, E., Drapkin, M. S., Jablons, D. M., & Cano, G. (1993). Pylephlebitis associated with diverticulitis. Southern Medical Journal, 86(5), 578-80.
Perez-Cruet MJ, et al. Pylephlebitis Associated With Diverticulitis. South Med J. 1993;86(5):578-80. PubMed PMID: 8488411.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pylephlebitis associated with diverticulitis. AU - Perez-Cruet,M J, AU - Grable,E, AU - Drapkin,M S, AU - Jablons,D M, AU - Cano,G, PY - 1993/5/1/pubmed PY - 1993/5/1/medline PY - 1993/5/1/entrez SP - 578 EP - 80 JF - Southern medical journal JO - South Med J VL - 86 IS - 5 N2 - We have reported the cases of two patients who had acute pylephlebitis associated with portal vein thrombosis and septic hepatic emboli as a result of right colonic diverticulitis. Although rare, pylephlebitis is a treatable but often lethal complication of intra-abdominal sepsis. Several bacterial pathogens, especially Escherichia coli are associated with pylephlebitis. Early suspicion and prompt antibiotic therapy can lead to resolution of portal vein thrombosis and hepatic abscess formation, resulting in full recovery for the patient. Surgery may not be required. Our two patients received ampicillin--the best first-line drug--until specific antibiotic therapy could be given. Early administration of a broad spectrum antibiotic is essential. SN - 0038-4348 UR - https://www.unboundmedicine.com/medline/citation/8488411/Pylephlebitis_associated_with_diverticulitis_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=8488411.ui DB - PRIME DP - Unbound Medicine ER -