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Anergic disseminated toxoplasmosis in a patient with the acquired immunodeficiency syndrome.

Abstract

Cerebral toxoplasmosis is the most common cause of focal brain disease in patients with the acquired immunodeficiency syndrome. A 24-year-old human immunodeficiency virus-infected woman with two previous episodes of Pneumocystis carinii pneumonia presented with diarrhea and fever. Despite antibiotic treatment, septic shock developed, and she died 3 weeks after the symptoms began. Histologic and histochemical studies revealed an anergic toxoplasmosis with dissemination in all examined organs. There were multiple foci of toxoplasmic cysts and free tachyzoites, sometimes with minute areas of necrosis, but no inflammatory reaction at all. Since effective treatment of toxoplasmosis is available, the occurrence of this rare form of toxoplasmosis should be kept in mind.

Authors+Show Affiliations

,

Institute of Pathology, Auguste-Viktoria-Krankenhaus, Berlin, Germany.

,

Source

MeSH

AIDS Dementia Complex
Adult
Animals
Cerebral Cortex
Female
Humans
Toxoplasma
Toxoplasmosis, Cerebral

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

8489347

Citation

Artigas, J, et al. "Anergic Disseminated Toxoplasmosis in a Patient With the Acquired Immunodeficiency Syndrome." Archives of Pathology & Laboratory Medicine, vol. 117, no. 5, 1993, pp. 540-1.
Artigas J, Grosse G, Niedobitek F. Anergic disseminated toxoplasmosis in a patient with the acquired immunodeficiency syndrome. Arch Pathol Lab Med. 1993;117(5):540-1.
Artigas, J., Grosse, G., & Niedobitek, F. (1993). Anergic disseminated toxoplasmosis in a patient with the acquired immunodeficiency syndrome. Archives of Pathology & Laboratory Medicine, 117(5), pp. 540-1.
Artigas J, Grosse G, Niedobitek F. Anergic Disseminated Toxoplasmosis in a Patient With the Acquired Immunodeficiency Syndrome. Arch Pathol Lab Med. 1993;117(5):540-1. PubMed PMID: 8489347.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Anergic disseminated toxoplasmosis in a patient with the acquired immunodeficiency syndrome. AU - Artigas,J, AU - Grosse,G, AU - Niedobitek,F, PY - 1993/5/1/pubmed PY - 1993/5/1/medline PY - 1993/5/1/entrez SP - 540 EP - 1 JF - Archives of pathology & laboratory medicine JO - Arch. Pathol. Lab. Med. VL - 117 IS - 5 N2 - Cerebral toxoplasmosis is the most common cause of focal brain disease in patients with the acquired immunodeficiency syndrome. A 24-year-old human immunodeficiency virus-infected woman with two previous episodes of Pneumocystis carinii pneumonia presented with diarrhea and fever. Despite antibiotic treatment, septic shock developed, and she died 3 weeks after the symptoms began. Histologic and histochemical studies revealed an anergic toxoplasmosis with dissemination in all examined organs. There were multiple foci of toxoplasmic cysts and free tachyzoites, sometimes with minute areas of necrosis, but no inflammatory reaction at all. Since effective treatment of toxoplasmosis is available, the occurrence of this rare form of toxoplasmosis should be kept in mind. SN - 0003-9985 UR - https://www.unboundmedicine.com/medline/citation/8489347/Anergic_disseminated_toxoplasmosis_in_a_patient_with_the_acquired_immunodeficiency_syndrome_ DB - PRIME DP - Unbound Medicine ER -