Tags

Type your tag names separated by a space and hit enter

Prevalence of latent portasystemic encephalopathy in an unselected population of patients with liver cirrhosis in general practice.
Z Gastroenterol. 1993 Apr; 31(4):231-4.ZG

Abstract

To evaluate the prevalence of latent PSE in unselected ambulatory patients with liver cirrhosis practicing physicians were asked to perform two non instrumental psychometric tests (number connection test and line tracing test) on patients with clinical signs of liver cirrhosis and portal hypertension. Tests were repeated after 8 weeks of treatment with Lactulose in those patients considered to have latent PSE at the initial evaluation. 296 physicians tested a total of 783 patients, 771 of these could be evaluated. 551 patients (71.5%) were considered to have latent PSE. There was a significant correlation between psychometric test results and biochemical parameters related to liver function. Repeat testing after 8 weeks treatment with Lactulose revealed definite improvement of psychometric test results in 88% of the patients. At the final evaluation only about 30% of the patients fulfilled the criteria of latent PSE. There was a statistically significant albeit weak correlation between changes in biochemical parameters and psychometric improvement. Psychometric testing with simple non instrumental tests proved to be practicable in the office setting.

Authors+Show Affiliations

II. Medizinische Klinik, Diakoniekrankenhaus, Rotenburg, Wümme.No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8493802

Citation

Schomerus, H, and J Schreiegg. "Prevalence of Latent Portasystemic Encephalopathy in an Unselected Population of Patients With Liver Cirrhosis in General Practice." Zeitschrift Fur Gastroenterologie, vol. 31, no. 4, 1993, pp. 231-4.
Schomerus H, Schreiegg J. Prevalence of latent portasystemic encephalopathy in an unselected population of patients with liver cirrhosis in general practice. Z Gastroenterol. 1993;31(4):231-4.
Schomerus, H., & Schreiegg, J. (1993). Prevalence of latent portasystemic encephalopathy in an unselected population of patients with liver cirrhosis in general practice. Zeitschrift Fur Gastroenterologie, 31(4), 231-4.
Schomerus H, Schreiegg J. Prevalence of Latent Portasystemic Encephalopathy in an Unselected Population of Patients With Liver Cirrhosis in General Practice. Z Gastroenterol. 1993;31(4):231-4. PubMed PMID: 8493802.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence of latent portasystemic encephalopathy in an unselected population of patients with liver cirrhosis in general practice. AU - Schomerus,H, AU - Schreiegg,J, PY - 1993/4/1/pubmed PY - 1993/4/1/medline PY - 1993/4/1/entrez SP - 231 EP - 4 JF - Zeitschrift fur Gastroenterologie JO - Z Gastroenterol VL - 31 IS - 4 N2 - To evaluate the prevalence of latent PSE in unselected ambulatory patients with liver cirrhosis practicing physicians were asked to perform two non instrumental psychometric tests (number connection test and line tracing test) on patients with clinical signs of liver cirrhosis and portal hypertension. Tests were repeated after 8 weeks of treatment with Lactulose in those patients considered to have latent PSE at the initial evaluation. 296 physicians tested a total of 783 patients, 771 of these could be evaluated. 551 patients (71.5%) were considered to have latent PSE. There was a significant correlation between psychometric test results and biochemical parameters related to liver function. Repeat testing after 8 weeks treatment with Lactulose revealed definite improvement of psychometric test results in 88% of the patients. At the final evaluation only about 30% of the patients fulfilled the criteria of latent PSE. There was a statistically significant albeit weak correlation between changes in biochemical parameters and psychometric improvement. Psychometric testing with simple non instrumental tests proved to be practicable in the office setting. SN - 0044-2771 UR - https://www.unboundmedicine.com/medline/citation/8493802/Prevalence_of_latent_portasystemic_encephalopathy_in_an_unselected_population_of_patients_with_liver_cirrhosis_in_general_practice_ L2 - https://medlineplus.gov/cirrhosis.html DB - PRIME DP - Unbound Medicine ER -