Tags

Type your tag names separated by a space and hit enter

Cost effectiveness of noninvasive oxygen saturation measurement during exercise for the diagnosis of Pneumocystis carinii pneumonia.
Am Rev Respir Dis. 1993 Jun; 147(6 Pt 1):1360-3.AR

Abstract

We assessed (1) the sensitivity and specificity of exercise oxygen saturation measurement (EOS) for the diagnosis of Pneumocystis carinii pneumonia (PCP); and (2) the cost of introducing this indirect diagnostic test compared with that of standard diagnostic strategies for PCP. In a prospective study, 85 HIV-infected patients with suspected PCP underwent EOS, followed by induced sputum (IS) and bronchoalveolar lavage (BAL) if IS was negative for P. carinii. The prevalence of PCP was 0.22, the sensitivity of IS was 0.6, and its specificity was perfect. The cost ratios of IS to BAL and EOS to BAL were 0.1 and 0.2, respectively. A desaturation of three points was the best cutoff point, giving perfect sensitivity and a specificity of 0.77. The cost analysis showed that the introduction of EOS into diagnostic strategies for PCP is highly justified when the local prevalence is low. Exercise oxygen saturation measurement is simple and safe, and the results are available rapidly; its sensitivity is perfect and its specificity good. Its economic utility depends on its cost and the local prevalence of PCP in the test population.

Authors+Show Affiliations

Pneumology Service, Hôpital Saint Antoine, Paris.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

8503546

Citation

Chouaid, C, et al. "Cost Effectiveness of Noninvasive Oxygen Saturation Measurement During Exercise for the Diagnosis of Pneumocystis Carinii Pneumonia." The American Review of Respiratory Disease, vol. 147, no. 6 Pt 1, 1993, pp. 1360-3.
Chouaid C, Maillard D, Housset B, et al. Cost effectiveness of noninvasive oxygen saturation measurement during exercise for the diagnosis of Pneumocystis carinii pneumonia. Am Rev Respir Dis. 1993;147(6 Pt 1):1360-3.
Chouaid, C., Maillard, D., Housset, B., Febvre, M., Zaoui, D., & Lebeau, B. (1993). Cost effectiveness of noninvasive oxygen saturation measurement during exercise for the diagnosis of Pneumocystis carinii pneumonia. The American Review of Respiratory Disease, 147(6 Pt 1), 1360-3.
Chouaid C, et al. Cost Effectiveness of Noninvasive Oxygen Saturation Measurement During Exercise for the Diagnosis of Pneumocystis Carinii Pneumonia. Am Rev Respir Dis. 1993;147(6 Pt 1):1360-3. PubMed PMID: 8503546.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cost effectiveness of noninvasive oxygen saturation measurement during exercise for the diagnosis of Pneumocystis carinii pneumonia. AU - Chouaid,C, AU - Maillard,D, AU - Housset,B, AU - Febvre,M, AU - Zaoui,D, AU - Lebeau,B, PY - 1993/6/1/pubmed PY - 1993/6/1/medline PY - 1993/6/1/entrez SP - 1360 EP - 3 JF - The American review of respiratory disease JO - Am Rev Respir Dis VL - 147 IS - 6 Pt 1 N2 - We assessed (1) the sensitivity and specificity of exercise oxygen saturation measurement (EOS) for the diagnosis of Pneumocystis carinii pneumonia (PCP); and (2) the cost of introducing this indirect diagnostic test compared with that of standard diagnostic strategies for PCP. In a prospective study, 85 HIV-infected patients with suspected PCP underwent EOS, followed by induced sputum (IS) and bronchoalveolar lavage (BAL) if IS was negative for P. carinii. The prevalence of PCP was 0.22, the sensitivity of IS was 0.6, and its specificity was perfect. The cost ratios of IS to BAL and EOS to BAL were 0.1 and 0.2, respectively. A desaturation of three points was the best cutoff point, giving perfect sensitivity and a specificity of 0.77. The cost analysis showed that the introduction of EOS into diagnostic strategies for PCP is highly justified when the local prevalence is low. Exercise oxygen saturation measurement is simple and safe, and the results are available rapidly; its sensitivity is perfect and its specificity good. Its economic utility depends on its cost and the local prevalence of PCP in the test population. SN - 0003-0805 UR - https://www.unboundmedicine.com/medline/citation/8503546/Cost_effectiveness_of_noninvasive_oxygen_saturation_measurement_during_exercise_for_the_diagnosis_of_Pneumocystis_carinii_pneumonia_ L2 - https://www.atsjournals.org/doi/10.1164/ajrccm/147.6_Pt_1.1360?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -