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Glycerol effect on the guinea pig tectorial membrane.
Eur Arch Otorhinolaryngol 1993; 250(2):88-91EA

Abstract

The tectorial membrane (Tm) of guinea pigs has been found to have an altered organization of its matrix fibers in response to intravenously administered glycerol. Following treatment, the Tm middle zone shows an increase in waviness and clumping of fibers in non-hydropic and several hydropic ears in contrast to non-treated control ears. Residue of the internal sulcus cells occasionally fills the subtectorial space. In the present study, additional investigations were performed with scanning electron microscopy in order to study the relationship between the Tm and the organ of Corti, as well as the relationship between Hensen's stripe and the inner hair cell. Present findings provide evidence for a connection between the inner hair cell stereocilia and Hensen's stripe which may be the molecular basis for the modulation of hearing during the glycerol test in a patient with Meniere's disease.

Authors+Show Affiliations

Department of Otorhinolaryngology, Heinrich-Heine-University, Düsseldorf, Germany.No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8507471

Citation

Meyer zum Gottesberge, A M., and S Tsujikawa. "Glycerol Effect On the Guinea Pig Tectorial Membrane." European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated With the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, vol. 250, no. 2, 1993, pp. 88-91.
Meyer zum Gottesberge AM, Tsujikawa S. Glycerol effect on the guinea pig tectorial membrane. Eur Arch Otorhinolaryngol. 1993;250(2):88-91.
Meyer zum Gottesberge, A. M., & Tsujikawa, S. (1993). Glycerol effect on the guinea pig tectorial membrane. European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated With the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 250(2), pp. 88-91.
Meyer zum Gottesberge AM, Tsujikawa S. Glycerol Effect On the Guinea Pig Tectorial Membrane. Eur Arch Otorhinolaryngol. 1993;250(2):88-91. PubMed PMID: 8507471.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Glycerol effect on the guinea pig tectorial membrane. AU - Meyer zum Gottesberge,A M, AU - Tsujikawa,S, PY - 1993/1/1/pubmed PY - 1993/1/1/medline PY - 1993/1/1/entrez SP - 88 EP - 91 JF - European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery JO - Eur Arch Otorhinolaryngol VL - 250 IS - 2 N2 - The tectorial membrane (Tm) of guinea pigs has been found to have an altered organization of its matrix fibers in response to intravenously administered glycerol. Following treatment, the Tm middle zone shows an increase in waviness and clumping of fibers in non-hydropic and several hydropic ears in contrast to non-treated control ears. Residue of the internal sulcus cells occasionally fills the subtectorial space. In the present study, additional investigations were performed with scanning electron microscopy in order to study the relationship between the Tm and the organ of Corti, as well as the relationship between Hensen's stripe and the inner hair cell. Present findings provide evidence for a connection between the inner hair cell stereocilia and Hensen's stripe which may be the molecular basis for the modulation of hearing during the glycerol test in a patient with Meniere's disease. SN - 0937-4477 UR - https://www.unboundmedicine.com/medline/citation/8507471/Glycerol_effect_on_the_guinea_pig_tectorial_membrane_ DB - PRIME DP - Unbound Medicine ER -