Tags

Type your tag names separated by a space and hit enter

Menstrual disorders in patients with chronic renal failure.
East Afr Med J. 1993 Jan; 70(1):6-9.EA

Abstract

Forty females, age 14 to 35 years (mean 28.6 years) with chronic renal failure (CRF) were included in the study. Their menstrual patterns were noted. The function of their hypothalamo-pituitary-ovarian axis was assessed by the serum levels of follicle stimulating hormone (FSH), Luteinising hormone (LH), prolactin (PrL), estradiol (E2) and progesterone (P) at different phases of the menstrual cycle in patients who continued to have normal menses (Group 1) and at weekly intervals for six weeks in patients with menstrual disturbances (Group II). The mean hormone levels during the initial contact Luteal phase in group I were FSH 12.0 IU/L (N, 1.0-3.0 IU/L), LH 1.8IU/L (N 1.5-101U/L), PrL 652mIU/L (N, 100-600 mIU/L) mE2 160 pmol/L (N 400-1400 pmol/L) and P5 nmol/L (N 14-60 nmol/L) for group I. Corresponding values for group II were 1.2, 10.3, 250, 600 and 3.0 in relevant units. All patients (fourteen) with end stage renal disease (ESRD) had amenorrhoae. On the other hand, most patients with stable CRF (22/26) had normal menses. Following initiation of therapy (conservative or dialytic), there was no significant alteration in the hormonal profile or menstrual pattern. We conclude that other factors apart from the hormonal imbalances, may be responsible for the menstrual disturbances noted in patients with CRF.

Authors+Show Affiliations

Aga Khan Hospital, Nairobi.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8513732

Citation

Otieno, M R., et al. "Menstrual Disorders in Patients With Chronic Renal Failure." East African Medical Journal, vol. 70, no. 1, 1993, pp. 6-9.
Otieno MR, McLigeyo SO, Kigondu CS, et al. Menstrual disorders in patients with chronic renal failure. East Afr Med J. 1993;70(1):6-9.
Otieno, M. R., McLigeyo, S. O., Kigondu, C. S., & Rogo, K. O. (1993). Menstrual disorders in patients with chronic renal failure. East African Medical Journal, 70(1), 6-9.
Otieno MR, et al. Menstrual Disorders in Patients With Chronic Renal Failure. East Afr Med J. 1993;70(1):6-9. PubMed PMID: 8513732.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Menstrual disorders in patients with chronic renal failure. AU - Otieno,M R, AU - McLigeyo,S O, AU - Kigondu,C S, AU - Rogo,K O, PY - 1993/1/1/pubmed PY - 1993/1/1/medline PY - 1993/1/1/entrez SP - 6 EP - 9 JF - East African medical journal JO - East Afr Med J VL - 70 IS - 1 N2 - Forty females, age 14 to 35 years (mean 28.6 years) with chronic renal failure (CRF) were included in the study. Their menstrual patterns were noted. The function of their hypothalamo-pituitary-ovarian axis was assessed by the serum levels of follicle stimulating hormone (FSH), Luteinising hormone (LH), prolactin (PrL), estradiol (E2) and progesterone (P) at different phases of the menstrual cycle in patients who continued to have normal menses (Group 1) and at weekly intervals for six weeks in patients with menstrual disturbances (Group II). The mean hormone levels during the initial contact Luteal phase in group I were FSH 12.0 IU/L (N, 1.0-3.0 IU/L), LH 1.8IU/L (N 1.5-101U/L), PrL 652mIU/L (N, 100-600 mIU/L) mE2 160 pmol/L (N 400-1400 pmol/L) and P5 nmol/L (N 14-60 nmol/L) for group I. Corresponding values for group II were 1.2, 10.3, 250, 600 and 3.0 in relevant units. All patients (fourteen) with end stage renal disease (ESRD) had amenorrhoae. On the other hand, most patients with stable CRF (22/26) had normal menses. Following initiation of therapy (conservative or dialytic), there was no significant alteration in the hormonal profile or menstrual pattern. We conclude that other factors apart from the hormonal imbalances, may be responsible for the menstrual disturbances noted in patients with CRF. SN - 0012-835X UR - https://www.unboundmedicine.com/medline/citation/8513732/Menstrual_disorders_in_patients_with_chronic_renal_failure_ L2 - https://medlineplus.gov/kidneyfailure.html DB - PRIME DP - Unbound Medicine ER -