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The association between oral leukoplakia and use of tobacco, alcohol and khat based on relative risks assessment in Kenya.
Eur J Oral Sci 1995; 103(5):268-73EJ

Abstract

A case-control study was conducted to determine the significance of tobacco, alcohol and khat (Catha edulis) chewing habits in the development of oral leukoplakia among Kenyans aged 15 yr and over. In a house-to-house survey, 85 cases and 141 controls matched for sex, age and cluster origin was identified and compared for these risk factors. Smoking unprocessed tobacco (Kiraiku) with a relative risk (RR) of 10.0 (95% confidence interval (CI) = 2.9-38.4) and smoking cigarettes (RR = 8.4; 95% CI = 4.1-17.4) were the most significant factors. While the RR associated with smoking cigarettes alone was 4.5 (95% CI = 1.9-10.8), smoking of both products (RR = 15.2) suggested probable synergy or additive effects. Oral leukoplakia in 18 cases could not be attributed to smoking tobacco. Commercial beer, wines and spirits were relatively weak, but statistically significant, risk factors. Traditional beer, khat and chilies were not significantly associated with oral leukoplakia.

Authors+Show Affiliations

University of Nairobi, College of Health Sciences, Department of Dental Surgery, Kenya.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

8521116

Citation

Macigo, F G., et al. "The Association Between Oral Leukoplakia and Use of Tobacco, Alcohol and Khat Based On Relative Risks Assessment in Kenya." European Journal of Oral Sciences, vol. 103, no. 5, 1995, pp. 268-73.
Macigo FG, Mwaniki DL, Guthua SW. The association between oral leukoplakia and use of tobacco, alcohol and khat based on relative risks assessment in Kenya. Eur J Oral Sci. 1995;103(5):268-73.
Macigo, F. G., Mwaniki, D. L., & Guthua, S. W. (1995). The association between oral leukoplakia and use of tobacco, alcohol and khat based on relative risks assessment in Kenya. European Journal of Oral Sciences, 103(5), pp. 268-73.
Macigo FG, Mwaniki DL, Guthua SW. The Association Between Oral Leukoplakia and Use of Tobacco, Alcohol and Khat Based On Relative Risks Assessment in Kenya. Eur J Oral Sci. 1995;103(5):268-73. PubMed PMID: 8521116.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The association between oral leukoplakia and use of tobacco, alcohol and khat based on relative risks assessment in Kenya. AU - Macigo,F G, AU - Mwaniki,D L, AU - Guthua,S W, PY - 1995/10/1/pubmed PY - 1995/10/1/medline PY - 1995/10/1/entrez SP - 268 EP - 73 JF - European journal of oral sciences JO - Eur. J. Oral Sci. VL - 103 IS - 5 N2 - A case-control study was conducted to determine the significance of tobacco, alcohol and khat (Catha edulis) chewing habits in the development of oral leukoplakia among Kenyans aged 15 yr and over. In a house-to-house survey, 85 cases and 141 controls matched for sex, age and cluster origin was identified and compared for these risk factors. Smoking unprocessed tobacco (Kiraiku) with a relative risk (RR) of 10.0 (95% confidence interval (CI) = 2.9-38.4) and smoking cigarettes (RR = 8.4; 95% CI = 4.1-17.4) were the most significant factors. While the RR associated with smoking cigarettes alone was 4.5 (95% CI = 1.9-10.8), smoking of both products (RR = 15.2) suggested probable synergy or additive effects. Oral leukoplakia in 18 cases could not be attributed to smoking tobacco. Commercial beer, wines and spirits were relatively weak, but statistically significant, risk factors. Traditional beer, khat and chilies were not significantly associated with oral leukoplakia. SN - 0909-8836 UR - https://www.unboundmedicine.com/medline/citation/8521116/The_association_between_oral_leukoplakia_and_use_of_tobacco_alcohol_and_khat_based_on_relative_risks_assessment_in_Kenya_ DB - PRIME DP - Unbound Medicine ER -