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Two unusual cases of kwashiorkor: can protein deficiency explain the mystery?

Abstract

Two children with unusual features of kwashiorkor are reported. One, an exclusively breastfed 7-month-old girl, had been admitted earlier, treated for pneumonia and discharged 3 weeks before she presented with kwashiorkor. The other was an identical twin who was admitted for kwashiorkor and gastro-enteritis. The twin sister was underweight but relatively well. Both children died. Potent aflatoxins were detected in the organs of these children on post-mortem examination. The occurrence of kwashiorkor in a fully breastfed infant and in an identical twin does not accord with the extant belief that the aetiology of kwashiorkor is wholly nutritional, but suggests a disease probably of multifactorial origin.

Authors+Show Affiliations

,

Department of Paediatrics and Child Health, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria.

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Source

Annals of tropical paediatrics 15:3 1995 Sep pg 217-9

MeSH

Aflatoxins
Breast Feeding
Diagnosis, Differential
Diseases in Twins
Female
Humans
Infant
Kwashiorkor
Nigeria
Protein Deficiency
Tissue Distribution

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

8534040

Citation

Oyelami, O A., et al. "Two Unusual Cases of Kwashiorkor: Can Protein Deficiency Explain the Mystery?" Annals of Tropical Paediatrics, vol. 15, no. 3, 1995, pp. 217-9.
Oyelami OA, Maxwell SM, Aladekomo TA, et al. Two unusual cases of kwashiorkor: can protein deficiency explain the mystery? Ann Trop Paediatr. 1995;15(3):217-9.
Oyelami, O. A., Maxwell, S. M., Aladekomo, T. A., & Adelusola, K. A. (1995). Two unusual cases of kwashiorkor: can protein deficiency explain the mystery? Annals of Tropical Paediatrics, 15(3), pp. 217-9.
Oyelami OA, et al. Two Unusual Cases of Kwashiorkor: Can Protein Deficiency Explain the Mystery. Ann Trop Paediatr. 1995;15(3):217-9. PubMed PMID: 8534040.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Two unusual cases of kwashiorkor: can protein deficiency explain the mystery? AU - Oyelami,O A, AU - Maxwell,S M, AU - Aladekomo,T A, AU - Adelusola,K A, PY - 1995/9/1/pubmed PY - 1995/9/1/medline PY - 1995/9/1/entrez SP - 217 EP - 9 JF - Annals of tropical paediatrics JO - Ann Trop Paediatr VL - 15 IS - 3 N2 - Two children with unusual features of kwashiorkor are reported. One, an exclusively breastfed 7-month-old girl, had been admitted earlier, treated for pneumonia and discharged 3 weeks before she presented with kwashiorkor. The other was an identical twin who was admitted for kwashiorkor and gastro-enteritis. The twin sister was underweight but relatively well. Both children died. Potent aflatoxins were detected in the organs of these children on post-mortem examination. The occurrence of kwashiorkor in a fully breastfed infant and in an identical twin does not accord with the extant belief that the aetiology of kwashiorkor is wholly nutritional, but suggests a disease probably of multifactorial origin. SN - 0272-4936 UR - https://www.unboundmedicine.com/medline/citation/8534040/Two_unusual_cases_of_kwashiorkor:_can_protein_deficiency_explain_the_mystery DB - PRIME DP - Unbound Medicine ER -