Tags

Type your tag names separated by a space and hit enter

Toward salivary-urinary chronosensitivity testing: chronomes of OVX1, M-CSF and CA130.
In Vivo. 1995 Jul-Aug; 9(4):407-12.V

Abstract

Several rhythmic components were previously mapped for salivary and/or urinary CA125 and CA130. On the background of such reference standards, OVX1 and M-CSF were assayed on 242 urine samples and 160 saliva samples provided by a 71-year-old patient with a Müllerian/ovarian adenocarcinoma. Serum OVX1 correlates with serum CA125 (P = 0.002); when circulating CA125 concentrations decreased (from 122 to 14 U/ml), the urinary excretion rate of OVX1 decreased (P = 0.005), whereas the urinary excretion rate of CA125 increased (P < 0.001). Salivary OVX1 and urinary M-CSF show ultradian variations (with a frequency of one cycle in 14-17 hours), which could be utilized to guide treatment timing targeted first to optimize treatment efficacy and as a second consideration to minimize treatment toxicity.

Authors+Show Affiliations

Duke University Medical Center, Durham, North Carolina, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

8555442

Citation

Xu, F, et al. "Toward Salivary-urinary Chronosensitivity Testing: Chronomes of OVX1, M-CSF and CA130." In Vivo (Athens, Greece), vol. 9, no. 4, 1995, pp. 407-12.
Xu F, Yu Y, Bast RC, et al. Toward salivary-urinary chronosensitivity testing: chronomes of OVX1, M-CSF and CA130. In Vivo. 1995;9(4):407-12.
Xu, F., Yu, Y., Bast, R. C., Cornélissen, G., Fujii, S., Takagi, M., O'Brien, T., & Halberg, F. (1995). Toward salivary-urinary chronosensitivity testing: chronomes of OVX1, M-CSF and CA130. In Vivo (Athens, Greece), 9(4), 407-12.
Xu F, et al. Toward Salivary-urinary Chronosensitivity Testing: Chronomes of OVX1, M-CSF and CA130. In Vivo. 1995 Jul-Aug;9(4):407-12. PubMed PMID: 8555442.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Toward salivary-urinary chronosensitivity testing: chronomes of OVX1, M-CSF and CA130. AU - Xu,F, AU - Yu,Y, AU - Bast,R C,Jr AU - Cornélissen,G, AU - Fujii,S, AU - Takagi,M, AU - O'Brien,T, AU - Halberg,F, PY - 1995/7/1/pubmed PY - 2001/3/28/medline PY - 1995/7/1/entrez SP - 407 EP - 12 JF - In vivo (Athens, Greece) JO - In Vivo VL - 9 IS - 4 N2 - Several rhythmic components were previously mapped for salivary and/or urinary CA125 and CA130. On the background of such reference standards, OVX1 and M-CSF were assayed on 242 urine samples and 160 saliva samples provided by a 71-year-old patient with a Müllerian/ovarian adenocarcinoma. Serum OVX1 correlates with serum CA125 (P = 0.002); when circulating CA125 concentrations decreased (from 122 to 14 U/ml), the urinary excretion rate of OVX1 decreased (P = 0.005), whereas the urinary excretion rate of CA125 increased (P < 0.001). Salivary OVX1 and urinary M-CSF show ultradian variations (with a frequency of one cycle in 14-17 hours), which could be utilized to guide treatment timing targeted first to optimize treatment efficacy and as a second consideration to minimize treatment toxicity. SN - 0258-851X UR - https://www.unboundmedicine.com/medline/citation/8555442/Toward_salivary_urinary_chronosensitivity_testing:_chronomes_of_OVX1_M_CSF_and_CA130_ L2 - https://antibodies.cancer.gov/detail/CPTC-CSF1-1 DB - PRIME DP - Unbound Medicine ER -