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Oral allergy syndrome induced by chestnut (Castanea sativa)
Ann Allergy Asthma Immunol. 1996 Jan; 76(1):37-40.AA

Abstract

BACKGROUND

Oral allergy syndrome is a distinctive type of allergy to food resulting from direct contact between food and the oral mucosa. Normally, it affects patients who are allergic to pollens. It can be challenged by testing for hypersensitivity to fresh fruit or vegetables in well-known associations. Oral allergy syndrome rarely occurs in patients with other types of allergies, or to food not associated with pollens. Only occasionally does chestnut cause hypersensitivity. There are only a few reported cases, depending on cross-reactivity in previously latex-hypersensitive patients. Oral allergy syndrome to chestnut in a patient with respiratory allergy to Dermatophagoides is therefore unusual and worth reporting.

OBJECTIVES

To describe the clinical features and their differences from previously reported cases and to analyze the techniques and methodologic problems related to in vivo and in vitro diagnosis.

METHODS

Case report. Skin tests with commercial and freshly made extracts and by the prick-by-prick method. Challenge test. Specific IgE antibody assay. Prausnitz-Küstner reaction.

RESULTS

The challenge with fresh food confirmed an oral allergy syndrome to chestnut. Clear symptoms of rhinoconjunctivitis and asthma set in as well. Skin tests with several commercial extracts and the prick-by-prick test were negative and so was specific IgE assay in serum by RAST and other immunoenzymatic methods. Skin prick test with a freshly prepared extract of fresh chestnut and the passive transfer reaction were positive.

CONCLUSIONS

The case of oral allergy syndrome to chestnut reported here appears to be a manifestation of immediate IgE-dependent hypersensitivity.

Authors

No affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

8564626

Citation

Antico, A. "Oral Allergy Syndrome Induced By Chestnut (Castanea Sativa)." Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology, vol. 76, no. 1, 1996, pp. 37-40.
Antico A. Oral allergy syndrome induced by chestnut (Castanea sativa). Ann Allergy Asthma Immunol. 1996;76(1):37-40.
Antico, A. (1996). Oral allergy syndrome induced by chestnut (Castanea sativa). Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology, 76(1), 37-40.
Antico A. Oral Allergy Syndrome Induced By Chestnut (Castanea Sativa). Ann Allergy Asthma Immunol. 1996;76(1):37-40. PubMed PMID: 8564626.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Oral allergy syndrome induced by chestnut (Castanea sativa) A1 - Antico,A, PY - 1996/1/1/pubmed PY - 1996/1/1/medline PY - 1996/1/1/entrez SP - 37 EP - 40 JF - Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology JO - Ann Allergy Asthma Immunol VL - 76 IS - 1 N2 - BACKGROUND: Oral allergy syndrome is a distinctive type of allergy to food resulting from direct contact between food and the oral mucosa. Normally, it affects patients who are allergic to pollens. It can be challenged by testing for hypersensitivity to fresh fruit or vegetables in well-known associations. Oral allergy syndrome rarely occurs in patients with other types of allergies, or to food not associated with pollens. Only occasionally does chestnut cause hypersensitivity. There are only a few reported cases, depending on cross-reactivity in previously latex-hypersensitive patients. Oral allergy syndrome to chestnut in a patient with respiratory allergy to Dermatophagoides is therefore unusual and worth reporting. OBJECTIVES: To describe the clinical features and their differences from previously reported cases and to analyze the techniques and methodologic problems related to in vivo and in vitro diagnosis. METHODS: Case report. Skin tests with commercial and freshly made extracts and by the prick-by-prick method. Challenge test. Specific IgE antibody assay. Prausnitz-Küstner reaction. RESULTS: The challenge with fresh food confirmed an oral allergy syndrome to chestnut. Clear symptoms of rhinoconjunctivitis and asthma set in as well. Skin tests with several commercial extracts and the prick-by-prick test were negative and so was specific IgE assay in serum by RAST and other immunoenzymatic methods. Skin prick test with a freshly prepared extract of fresh chestnut and the passive transfer reaction were positive. CONCLUSIONS: The case of oral allergy syndrome to chestnut reported here appears to be a manifestation of immediate IgE-dependent hypersensitivity. SN - 1081-1206 UR - https://www.unboundmedicine.com/medline/citation/8564626/Oral_allergy_syndrome_induced_by_chestnut__Castanea_sativa_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1081-1206(10)63404-7 DB - PRIME DP - Unbound Medicine ER -