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[Imported visceral leishmaniasis (kala azar) in a German infant].
Klin Padiatr. 1995 Nov-Dec; 207(6):347-9.KP

Abstract

We here report the case of a 1 4/12 year old girl with visceral leishmaniasis. Returning from a trip to Mallorca she presented with pancytopenia, splenomegaly and fever and was admitted to hospital with suspected malignancy. Diagnosis was established microscopically from bone marrow smear and confirmed by PCR-assisted amplification of leishmania-specific DNA from peripheral blood. Treatment was conducted with stibogluconate for 25 days. Defervescence and improvement of clinical symptoms was seen after 4 days of treatment. Infection due to Leishmania donovani can be acquired throughout the entire mediterranean area and should therefore be included in the differential diagnosis of suspected malignancies in patients with a history of travel to mediterranean countries. PCR proved to be a sensitive tool for establishing the diagnosis of visceral leishmaniasis.

Authors+Show Affiliations

Emeis M
Kinderklinik des Universitätsklinikum Rudolf Virchow, Standort Wedding, Freie Universität Berlin.
Liesenfeld O
No affiliation info available
Henze G
No affiliation info available
Meredith S
No affiliation info available
Schoone G
No affiliation info available
Stück B
No affiliation info available

MeSH

Antimony Sodium GluconateAntiprotozoal AgentsDiagnosis, DifferentialFemaleHumansInfantLeishmaniasis, VisceralPolymerase Chain ReactionSpainTravel

Pub Type(s)

Case Reports
English Abstract
Journal Article

Language

ger

PubMed ID

8569138

Citation

Emeis, M, et al. "[Imported Visceral Leishmaniasis (kala Azar) in a German Infant]." Klinische Padiatrie, vol. 207, no. 6, 1995, pp. 347-9.
Emeis M, Liesenfeld O, Henze G, et al. [Imported visceral leishmaniasis (kala azar) in a German infant]. Klin Padiatr. 1995;207(6):347-9.
Emeis, M., Liesenfeld, O., Henze, G., Meredith, S., Schoone, G., & Stück, B. (1995). [Imported visceral leishmaniasis (kala azar) in a German infant]. Klinische Padiatrie, 207(6), 347-9.
Emeis M, et al. [Imported Visceral Leishmaniasis (kala Azar) in a German Infant]. Klin Padiatr. 1995 Nov-Dec;207(6):347-9. PubMed PMID: 8569138.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Imported visceral leishmaniasis (kala azar) in a German infant]. AU - Emeis,M, AU - Liesenfeld,O, AU - Henze,G, AU - Meredith,S, AU - Schoone,G, AU - Stück,B, PY - 1995/11/1/pubmed PY - 1995/11/1/medline PY - 1995/11/1/entrez SP - 347 EP - 9 JF - Klinische Padiatrie JO - Klin Padiatr VL - 207 IS - 6 N2 - We here report the case of a 1 4/12 year old girl with visceral leishmaniasis. Returning from a trip to Mallorca she presented with pancytopenia, splenomegaly and fever and was admitted to hospital with suspected malignancy. Diagnosis was established microscopically from bone marrow smear and confirmed by PCR-assisted amplification of leishmania-specific DNA from peripheral blood. Treatment was conducted with stibogluconate for 25 days. Defervescence and improvement of clinical symptoms was seen after 4 days of treatment. Infection due to Leishmania donovani can be acquired throughout the entire mediterranean area and should therefore be included in the differential diagnosis of suspected malignancies in patients with a history of travel to mediterranean countries. PCR proved to be a sensitive tool for establishing the diagnosis of visceral leishmaniasis. SN - 0300-8630 UR - https://www.unboundmedicine.com/medline/citation/8569138/[Imported_visceral_leishmaniasis__kala_azar__in_a_German_infant]_ DB - PRIME DP - Unbound Medicine ER -