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Incidence of "chance" smear positivity among MB leprosy patients after MDT.
Indian J Lepr. 1995 Jul-Sep; 67(3):249-58.IJ

Abstract

Multidrug therapy (MDT) was introduced in 1982. Nine hundred eighty multibacillary (MB) leprosy patients had successfully completed the MDT administered for a minimum of two years or till skin smear negativity, whichever was later, as recommended by the World Health Organisation (WHO). During surveillance, 2.24% of them revealed presence of acid-fast bacilli (AFB) in the skin smear. They did not have any clinical evidence suggestive of relapse. Subsequent followup (without antileprosy chemotherapy) for periods ranging from one to eight years was uneventful. We have called this as "chance smear positivity" where a few bacilli, yet to be cleared by the immune system, were picked up by routine skin smear examination.

Authors+Show Affiliations

Department Branch of Epidemiology & Leprosy Control, Sehieffelin Leprosy Research & Training Centre, Karigiri.No affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

8576604

Citation

Vijayakumaran, P, et al. "Incidence of "chance" Smear Positivity Among MB Leprosy Patients After MDT." Indian Journal of Leprosy, vol. 67, no. 3, 1995, pp. 249-58.
Vijayakumaran P, Manimozhi N, Jesudasan K. Incidence of "chance" smear positivity among MB leprosy patients after MDT. Indian J Lepr. 1995;67(3):249-58.
Vijayakumaran, P., Manimozhi, N., & Jesudasan, K. (1995). Incidence of "chance" smear positivity among MB leprosy patients after MDT. Indian Journal of Leprosy, 67(3), 249-58.
Vijayakumaran P, Manimozhi N, Jesudasan K. Incidence of "chance" Smear Positivity Among MB Leprosy Patients After MDT. Indian J Lepr. 1995 Jul-Sep;67(3):249-58. PubMed PMID: 8576604.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Incidence of "chance" smear positivity among MB leprosy patients after MDT. AU - Vijayakumaran,P, AU - Manimozhi,N, AU - Jesudasan,K, PY - 1995/7/1/pubmed PY - 1995/7/1/medline PY - 1995/7/1/entrez SP - 249 EP - 58 JF - Indian journal of leprosy JO - Indian J Lepr VL - 67 IS - 3 N2 - Multidrug therapy (MDT) was introduced in 1982. Nine hundred eighty multibacillary (MB) leprosy patients had successfully completed the MDT administered for a minimum of two years or till skin smear negativity, whichever was later, as recommended by the World Health Organisation (WHO). During surveillance, 2.24% of them revealed presence of acid-fast bacilli (AFB) in the skin smear. They did not have any clinical evidence suggestive of relapse. Subsequent followup (without antileprosy chemotherapy) for periods ranging from one to eight years was uneventful. We have called this as "chance smear positivity" where a few bacilli, yet to be cleared by the immune system, were picked up by routine skin smear examination. SN - 0254-9395 UR - https://www.unboundmedicine.com/medline/citation/8576604/Incidence_of_"chance"_smear_positivity_among_MB_leprosy_patients_after_MDT_ DB - PRIME DP - Unbound Medicine ER -