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Correction of anemia and iron deficiency in vegetarians by administration of ascorbic acid.
Indian J Physiol Pharmacol. 1995 Oct; 39(4):403-6.IJ

Abstract

Twenty-eight strict vegetarians were given 500 mg ascorbic acid twice daily after lunch and dinner for two months. Hemoglobin and certain iron status parameters were measured before and after the treatment. Ascorbate treatment increased mean hemoglobin by 8%, serum iron by 17% and transferrin saturation by 23% and decreased total iron binding capacity by 7%. All these changes were statistically significant. The rise in serum ferritin was 12%. The serum protein or copper level did not indicate their dietary deficiency, while initial serum ascorbate level were low which rose by 60% on therapy. It is concluded that ascorbate supplementation is a better method of improving hematologic and iron status than iron salt administration.

Authors+Show Affiliations

Department of Biochemistry, S M S Medical College, Jaipur.No affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

8582755

Citation

Sharma, D C., and R Mathur. "Correction of Anemia and Iron Deficiency in Vegetarians By Administration of Ascorbic Acid." Indian Journal of Physiology and Pharmacology, vol. 39, no. 4, 1995, pp. 403-6.
Sharma DC, Mathur R. Correction of anemia and iron deficiency in vegetarians by administration of ascorbic acid. Indian J Physiol Pharmacol. 1995;39(4):403-6.
Sharma, D. C., & Mathur, R. (1995). Correction of anemia and iron deficiency in vegetarians by administration of ascorbic acid. Indian Journal of Physiology and Pharmacology, 39(4), 403-6.
Sharma DC, Mathur R. Correction of Anemia and Iron Deficiency in Vegetarians By Administration of Ascorbic Acid. Indian J Physiol Pharmacol. 1995;39(4):403-6. PubMed PMID: 8582755.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Correction of anemia and iron deficiency in vegetarians by administration of ascorbic acid. AU - Sharma,D C, AU - Mathur,R, PY - 1995/10/1/pubmed PY - 1995/10/1/medline PY - 1995/10/1/entrez SP - 403 EP - 6 JF - Indian journal of physiology and pharmacology JO - Indian J Physiol Pharmacol VL - 39 IS - 4 N2 - Twenty-eight strict vegetarians were given 500 mg ascorbic acid twice daily after lunch and dinner for two months. Hemoglobin and certain iron status parameters were measured before and after the treatment. Ascorbate treatment increased mean hemoglobin by 8%, serum iron by 17% and transferrin saturation by 23% and decreased total iron binding capacity by 7%. All these changes were statistically significant. The rise in serum ferritin was 12%. The serum protein or copper level did not indicate their dietary deficiency, while initial serum ascorbate level were low which rose by 60% on therapy. It is concluded that ascorbate supplementation is a better method of improving hematologic and iron status than iron salt administration. SN - 0019-5499 UR - https://www.unboundmedicine.com/medline/citation/8582755/Correction_of_anemia_and_iron_deficiency_in_vegetarians_by_administration_of_ascorbic_acid_ L2 - http://www.diseaseinfosearch.org/result/3873 DB - PRIME DP - Unbound Medicine ER -