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Induced abortions and risk of ectopic pregnancy.
Hum Reprod. 1995 Jul; 10(7):1841-4.HR

Abstract

The relationship between induced abortions and subsequent risk of ectopic pregnancy has been analysed using data from a case-control study conducted in Milan, Italy. The cases were 158 women with a diagnosis of ectopic pregnancy confirmed by laparoscopy or laparotomy, admitted to a network of university and general hospitals. Two control groups were selected. The first one (obstetric controls) included 243 women who gave birth at term (more than 37 weeks gestation) to healthy infants at the same hospitals where the cases had been identified. The second control group (non-obstetric controls) was a random sample of 158 women of comparable age interviewed in the same calendar period, admitted to hospital for a broad spectrum of acute, non-gynaecological or obstetric conditions. A total of 35 out of 158 cases (22%) reported one or more previous induced abortions; the corresponding figures were 29 out of 243 (12%) obstetric controls and 29 out of 158 (18%) non-obstetric ones. The risk of ectopic pregnancy was higher in women reporting induced abortions: the estimated multivariate relative risks (relative risk) for any induced abortions were 2.9 [95%, confidence interval (CI) 1.6-5.3] in comparison with obstetric controls and 2.5 (95% CI 1.2-5.0) in comparison with women admitted to hospital for other conditions. The risk increased with number of induced abortions, being, compared to women with no induced abortion, 13.1 (95% CI 3.2-54.5) and 3.8 (95% CI 1.1-12.7) in women reporting two or more induced abortions when the comparison groups were respectively obstetric and non-obstetric controls. This study shows an increased risk of ectopic pregnancy after induced abortion.(

ABSTRACT

TRUNCATED AT 250 WORDS)

Authors+Show Affiliations

Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

8582994

Citation

Parazzini, F, et al. "Induced Abortions and Risk of Ectopic Pregnancy." Human Reproduction (Oxford, England), vol. 10, no. 7, 1995, pp. 1841-4.
Parazzini F, Ferraroni M, Tozzi L, et al. Induced abortions and risk of ectopic pregnancy. Hum Reprod. 1995;10(7):1841-4.
Parazzini, F., Ferraroni, M., Tozzi, L., Ricci, E., Mezzopane, R., & La Vecchia, C. (1995). Induced abortions and risk of ectopic pregnancy. Human Reproduction (Oxford, England), 10(7), 1841-4.
Parazzini F, et al. Induced Abortions and Risk of Ectopic Pregnancy. Hum Reprod. 1995;10(7):1841-4. PubMed PMID: 8582994.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Induced abortions and risk of ectopic pregnancy. AU - Parazzini,F, AU - Ferraroni,M, AU - Tozzi,L, AU - Ricci,E, AU - Mezzopane,R, AU - La Vecchia,C, PY - 1995/7/1/pubmed PY - 1995/7/1/medline PY - 1995/7/1/entrez KW - Abortion, Induced KW - Biology KW - Case Control Studies KW - Clinical Research KW - Demographic Factors KW - Developed Countries KW - Diseases KW - Europe KW - Family Planning KW - Fertility Control, Postconception KW - Italy KW - Mediterranean Countries KW - Population KW - Population Characteristics KW - Pregnancy Complications KW - Pregnancy, Ectopic KW - Research Methodology KW - Research Report KW - Risk Factors KW - Southern Europe KW - Studies KW - Urban Population--women SP - 1841 EP - 4 JF - Human reproduction (Oxford, England) JO - Hum. Reprod. VL - 10 IS - 7 N2 - The relationship between induced abortions and subsequent risk of ectopic pregnancy has been analysed using data from a case-control study conducted in Milan, Italy. The cases were 158 women with a diagnosis of ectopic pregnancy confirmed by laparoscopy or laparotomy, admitted to a network of university and general hospitals. Two control groups were selected. The first one (obstetric controls) included 243 women who gave birth at term (more than 37 weeks gestation) to healthy infants at the same hospitals where the cases had been identified. The second control group (non-obstetric controls) was a random sample of 158 women of comparable age interviewed in the same calendar period, admitted to hospital for a broad spectrum of acute, non-gynaecological or obstetric conditions. A total of 35 out of 158 cases (22%) reported one or more previous induced abortions; the corresponding figures were 29 out of 243 (12%) obstetric controls and 29 out of 158 (18%) non-obstetric ones. The risk of ectopic pregnancy was higher in women reporting induced abortions: the estimated multivariate relative risks (relative risk) for any induced abortions were 2.9 [95%, confidence interval (CI) 1.6-5.3] in comparison with obstetric controls and 2.5 (95% CI 1.2-5.0) in comparison with women admitted to hospital for other conditions. The risk increased with number of induced abortions, being, compared to women with no induced abortion, 13.1 (95% CI 3.2-54.5) and 3.8 (95% CI 1.1-12.7) in women reporting two or more induced abortions when the comparison groups were respectively obstetric and non-obstetric controls. This study shows an increased risk of ectopic pregnancy after induced abortion.(ABSTRACT TRUNCATED AT 250 WORDS) SN - 0268-1161 UR - https://www.unboundmedicine.com/medline/citation/8582994/Induced_abortions_and_risk_of_ectopic_pregnancy_ L2 - https://academic.oup.com/humrep/article-lookup/doi/10.1093/oxfordjournals.humrep.a136188 DB - PRIME DP - Unbound Medicine ER -