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[Action of growth hormone releasing hormone (GHRH) on sleep EEG and nocturnal secretion of growth hormone, cortisol and ACTH in patients with major depression].
Wien Med Wochenschr. 1995; 145(17-18):499-500.WM

Abstract

In contrast to the effects of GHRH in young normal human subjects, in which repetitive i.v. administration of GHRH prompts an increase in the amount of slow wave sleep (SWS) and in GH secretion and blunting of cortisol release, both in young and in old patients with depression there is no effect on SWS and cortisol release after GHRH, while GH secretion is stimulated. We assume that HPA activity and SWS are inert to the influence of GHRH during acute depression because of a slight CRH overactivity, whereas GHRH exerts effects on GH secretion.

Authors+Show Affiliations

Max-Planck-Institut für Psychiatrie, München, Deutschland.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
English Abstract
Journal Article
Randomized Controlled Trial

Language

ger

PubMed ID

8588384

Citation

Frieboes, R M., et al. "[Action of Growth Hormone Releasing Hormone (GHRH) On Sleep EEG and Nocturnal Secretion of Growth Hormone, Cortisol and ACTH in Patients With Major Depression]." Wiener Medizinische Wochenschrift (1946), vol. 145, no. 17-18, 1995, pp. 499-500.
Frieboes RM, Schier T, Guldner J, et al. [Action of growth hormone releasing hormone (GHRH) on sleep EEG and nocturnal secretion of growth hormone, cortisol and ACTH in patients with major depression]. Wien Med Wochenschr. 1995;145(17-18):499-500.
Frieboes, R. M., Schier, T., Guldner, J., Colla-Müller, M., Murck, H., & Steiger, A. (1995). [Action of growth hormone releasing hormone (GHRH) on sleep EEG and nocturnal secretion of growth hormone, cortisol and ACTH in patients with major depression]. Wiener Medizinische Wochenschrift (1946), 145(17-18), 499-500.
Frieboes RM, et al. [Action of Growth Hormone Releasing Hormone (GHRH) On Sleep EEG and Nocturnal Secretion of Growth Hormone, Cortisol and ACTH in Patients With Major Depression]. Wien Med Wochenschr. 1995;145(17-18):499-500. PubMed PMID: 8588384.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Action of growth hormone releasing hormone (GHRH) on sleep EEG and nocturnal secretion of growth hormone, cortisol and ACTH in patients with major depression]. AU - Frieboes,R M, AU - Schier,T, AU - Guldner,J, AU - Colla-Müller,M, AU - Murck,H, AU - Steiger,A, PY - 1995/1/1/pubmed PY - 1995/1/1/medline PY - 1995/1/1/entrez SP - 499 EP - 500 JF - Wiener medizinische Wochenschrift (1946) JO - Wien Med Wochenschr VL - 145 IS - 17-18 N2 - In contrast to the effects of GHRH in young normal human subjects, in which repetitive i.v. administration of GHRH prompts an increase in the amount of slow wave sleep (SWS) and in GH secretion and blunting of cortisol release, both in young and in old patients with depression there is no effect on SWS and cortisol release after GHRH, while GH secretion is stimulated. We assume that HPA activity and SWS are inert to the influence of GHRH during acute depression because of a slight CRH overactivity, whereas GHRH exerts effects on GH secretion. SN - 0043-5341 UR - https://www.unboundmedicine.com/medline/citation/8588384/[Action_of_growth_hormone_releasing_hormone__GHRH__on_sleep_EEG_and_nocturnal_secretion_of_growth_hormone_cortisol_and_ACTH_in_patients_with_major_depression]_ L2 - http://www.diseaseinfosearch.org/result/2199 DB - PRIME DP - Unbound Medicine ER -