Tags

Type your tag names separated by a space and hit enter

Progressive osseous heteroplasia, uncommon cause of soft tissue ossification: a case report and review of the literature.
Pediatr Pathol Lab Med 1995 Sep-Oct; 15(5):813-27PP

Abstract

We report a case of an uncommon, recently described disease manifesting shortly after birth, characterized by extensive soft tissue calcification with ossification, progressive osseous heteroplasia. We describe the complex histopathologic patterns present in this case, discuss the main differential diagnoses that the surgical pathologist must consider when confronted by soft tissue ossification, and review the pertinent literature. We conclude that although the morphologic patterns of ossification in progressive osseous heteroplasia are complex and the involvement is extensive, the morphology of the lesions lacks diagnostic specificity. The diagnosis must be based on a consideration of the combined clinical data and radiologic and pathologic findings. This approach alone makes it possible to exclude a number of clinicopathologic entities that manifest with so-called osteoma cutis but whose associated lesions and genetic implications are different.

Authors+Show Affiliations

Department of Pathology, Children's Memorial Hospital, Chicago, Illinois 60614, USA.No affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Review

Language

eng

PubMed ID

8597867

Citation

Rodriguez-Jurado, R, et al. "Progressive Osseous Heteroplasia, Uncommon Cause of Soft Tissue Ossification: a Case Report and Review of the Literature." Pediatric Pathology & Laboratory Medicine : Journal of the Society for Pediatric Pathology, Affiliated With the International Paediatric Pathology Association, vol. 15, no. 5, 1995, pp. 813-27.
Rodriguez-Jurado R, Gonzalez-Crussi F, Poznanski AK. Progressive osseous heteroplasia, uncommon cause of soft tissue ossification: a case report and review of the literature. Pediatr Pathol Lab Med. 1995;15(5):813-27.
Rodriguez-Jurado, R., Gonzalez-Crussi, F., & Poznanski, A. K. (1995). Progressive osseous heteroplasia, uncommon cause of soft tissue ossification: a case report and review of the literature. Pediatric Pathology & Laboratory Medicine : Journal of the Society for Pediatric Pathology, Affiliated With the International Paediatric Pathology Association, 15(5), pp. 813-27.
Rodriguez-Jurado R, Gonzalez-Crussi F, Poznanski AK. Progressive Osseous Heteroplasia, Uncommon Cause of Soft Tissue Ossification: a Case Report and Review of the Literature. Pediatr Pathol Lab Med. 1995;15(5):813-27. PubMed PMID: 8597867.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Progressive osseous heteroplasia, uncommon cause of soft tissue ossification: a case report and review of the literature. AU - Rodriguez-Jurado,R, AU - Gonzalez-Crussi,F, AU - Poznanski,A K, PY - 1995/9/1/pubmed PY - 1995/9/1/medline PY - 1995/9/1/entrez SP - 813 EP - 27 JF - Pediatric pathology & laboratory medicine : journal of the Society for Pediatric Pathology, affiliated with the International Paediatric Pathology Association JO - Pediatr Pathol Lab Med VL - 15 IS - 5 N2 - We report a case of an uncommon, recently described disease manifesting shortly after birth, characterized by extensive soft tissue calcification with ossification, progressive osseous heteroplasia. We describe the complex histopathologic patterns present in this case, discuss the main differential diagnoses that the surgical pathologist must consider when confronted by soft tissue ossification, and review the pertinent literature. We conclude that although the morphologic patterns of ossification in progressive osseous heteroplasia are complex and the involvement is extensive, the morphology of the lesions lacks diagnostic specificity. The diagnosis must be based on a consideration of the combined clinical data and radiologic and pathologic findings. This approach alone makes it possible to exclude a number of clinicopathologic entities that manifest with so-called osteoma cutis but whose associated lesions and genetic implications are different. SN - 1077-1042 UR - https://www.unboundmedicine.com/medline/citation/8597867/Progressive_osseous_heteroplasia_uncommon_cause_of_soft_tissue_ossification:_a_case_report_and_review_of_the_literature_ L2 - http://www.diseaseinfosearch.org/result/5985 DB - PRIME DP - Unbound Medicine ER -