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Uriscreen, a rapid enzymatic urine screening test: useful predictor of significant bacteriuria in pregnancy.
Obstet Gynecol. 1996 Mar; 87(3):410-3.OG

Abstract

OBJECTIVE

To establish the reliability of a new rapid enzymatic screening test, the Uriscreen, in the detection of significant bacteriuria in pregnancy.

METHODS

During a 6-month period, from July 1 to December 30, 1993, 313 consecutive pregnant patients were evaluated. Randomly voided, midstream, clean-catch urine specimens were used. Each sample was tested by routine laboratory culture and four rapid screening tests: the nitrite and leukocyte esterase dipstick, microscopic examination for pyuria, and the Uriscreen test. Results of the four rapid tests were compared with those of the urine culture.

RESULTS

Twenty-four women (7.6%) had urine culture results indicating significant bacteriuria. The sensitivity of the nitrite test, the leukocyte esterase test, and a microscopic examination for pyuria was low (37, 52, and 56%, respectively). The Uriscreen test showed very high sensitivity (100%), lower specificity (81%), a high predictive value of negative results (100%), and a low positive predictive value (30%).

CONCLUSIONS

The Uriscreen test is a reliable alternative to culture screening of all pregnant patients. A policy of performing a urine culture during pregnancy only on patients with a positive Uriscreen test will save as much as 80% of unnecessary cultures.

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Authors+Show Affiliations

Hagay Z
Maternal-Fetal Medicine Unit, Department of Obstetrics and Gynecology, Kaplan Hospital, Rehovot, Israel.
Levy R
No affiliation info available
Miskin A
No affiliation info available
Milman D
No affiliation info available
Sharabi H
No affiliation info available
Insler V
No affiliation info available

MeSH

AdultBacteriuriaCarboxylic Ester HydrolasesClinical Enzyme TestsEvaluation Studies as TopicFemaleHumansPredictive Value of TestsPregnancyPregnancy Complications, InfectiousProspective StudiesReproducibility of ResultsUrinalysis

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

8598964

Citation

Hagay, Z, et al. "Uriscreen, a Rapid Enzymatic Urine Screening Test: Useful Predictor of Significant Bacteriuria in Pregnancy." Obstetrics and Gynecology, vol. 87, no. 3, 1996, pp. 410-3.
Hagay Z, Levy R, Miskin A, et al. Uriscreen, a rapid enzymatic urine screening test: useful predictor of significant bacteriuria in pregnancy. Obstet Gynecol. 1996;87(3):410-3.
Hagay, Z., Levy, R., Miskin, A., Milman, D., Sharabi, H., & Insler, V. (1996). Uriscreen, a rapid enzymatic urine screening test: useful predictor of significant bacteriuria in pregnancy. Obstetrics and Gynecology, 87(3), 410-3.
Hagay Z, et al. Uriscreen, a Rapid Enzymatic Urine Screening Test: Useful Predictor of Significant Bacteriuria in Pregnancy. Obstet Gynecol. 1996;87(3):410-3. PubMed PMID: 8598964.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Uriscreen, a rapid enzymatic urine screening test: useful predictor of significant bacteriuria in pregnancy. AU - Hagay,Z, AU - Levy,R, AU - Miskin,A, AU - Milman,D, AU - Sharabi,H, AU - Insler,V, PY - 1996/3/1/pubmed PY - 1996/3/1/medline PY - 1996/3/1/entrez SP - 410 EP - 3 JF - Obstetrics and gynecology JO - Obstet Gynecol VL - 87 IS - 3 N2 - OBJECTIVE: To establish the reliability of a new rapid enzymatic screening test, the Uriscreen, in the detection of significant bacteriuria in pregnancy. METHODS: During a 6-month period, from July 1 to December 30, 1993, 313 consecutive pregnant patients were evaluated. Randomly voided, midstream, clean-catch urine specimens were used. Each sample was tested by routine laboratory culture and four rapid screening tests: the nitrite and leukocyte esterase dipstick, microscopic examination for pyuria, and the Uriscreen test. Results of the four rapid tests were compared with those of the urine culture. RESULTS: Twenty-four women (7.6%) had urine culture results indicating significant bacteriuria. The sensitivity of the nitrite test, the leukocyte esterase test, and a microscopic examination for pyuria was low (37, 52, and 56%, respectively). The Uriscreen test showed very high sensitivity (100%), lower specificity (81%), a high predictive value of negative results (100%), and a low positive predictive value (30%). CONCLUSIONS: The Uriscreen test is a reliable alternative to culture screening of all pregnant patients. A policy of performing a urine culture during pregnancy only on patients with a positive Uriscreen test will save as much as 80% of unnecessary cultures. SN - 0029-7844 UR - https://www.unboundmedicine.com/medline/citation/8598964/Uriscreen_a_rapid_enzymatic_urine_screening_test:_useful_predictor_of_significant_bacteriuria_in_pregnancy_ L2 - https://linkinghub.elsevier.com/retrieve/pii/0029784495004513 DB - PRIME DP - Unbound Medicine ER -