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Notes on the apparent discordance of pulse oximetry and multi-wavelength haemoglobin photometry.
Acta Anaesthesiol Scand Suppl. 1995; 107:49-52.AA

Abstract

Multi-wavelength photometers, blood gas analysers and pulse oximeters are widely used to measure various oxygen-related quantities. The definitions of these quantities are not always correct. This paper gives insight in the various definitions for oxygen quantities. Furthermore, the possible influences of dyshaemoglobins and fetal haemoglobin on the accuracy of pulse oximetry are discussed. As pulse oximeters are constructed for the determination of arterial oxygen saturation, they should be validated with sample oxygen saturation values and not with the oxyhaemoglobin fraction. The influence of carboxyhaemoglobin is insubstantial over an oxygen saturation range of 0% to 100%. Through the presence of methaemoglobin, pulse oximetry will give an underestimation above 70% and an overestimation below 70% oxygen saturation. The influence of fetal haemoglobin is insignificant in the neonatal use of pulse oximetry, in the range of 75% to 100% arterial oxygen saturation. However, a pulse oximeter underestimates the arterial oxygen saturation at the 25% level with 5%, if the pulse oximeter has been calibrated in human adults. Such a low level of arterial oxygen saturation can be present in the fetus during labor.

Authors+Show Affiliations

Nijland R
Department of Obstetrics & Gynaecology, Faculty of Medical Sciences, University of Nijmegen, The Netherlands.
Jongsma HW
No affiliation info available
Nijhuis JG
No affiliation info available
Oeseburg B
No affiliation info available
Zijlstra WG
No affiliation info available

MeSH

AdultCalibrationCarboxyhemoglobinFemaleFetal HemoglobinHemoglobinsHumansInfant, NewbornLabor, ObstetricMethemoglobinOximetryOxygenOxyhemoglobinsPhotometryPregnancyReproducibility of Results

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8599297

Citation

Nijland, R, et al. "Notes On the Apparent Discordance of Pulse Oximetry and Multi-wavelength Haemoglobin Photometry." Acta Anaesthesiologica Scandinavica. Supplementum, vol. 107, 1995, pp. 49-52.
Nijland R, Jongsma HW, Nijhuis JG, et al. Notes on the apparent discordance of pulse oximetry and multi-wavelength haemoglobin photometry. Acta Anaesthesiol Scand Suppl. 1995;107:49-52.
Nijland, R., Jongsma, H. W., Nijhuis, J. G., Oeseburg, B., & Zijlstra, W. G. (1995). Notes on the apparent discordance of pulse oximetry and multi-wavelength haemoglobin photometry. Acta Anaesthesiologica Scandinavica. Supplementum, 107, 49-52.
Nijland R, et al. Notes On the Apparent Discordance of Pulse Oximetry and Multi-wavelength Haemoglobin Photometry. Acta Anaesthesiol Scand Suppl. 1995;107:49-52. PubMed PMID: 8599297.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Notes on the apparent discordance of pulse oximetry and multi-wavelength haemoglobin photometry. AU - Nijland,R, AU - Jongsma,H W, AU - Nijhuis,J G, AU - Oeseburg,B, AU - Zijlstra,W G, PY - 1995/1/1/pubmed PY - 1995/1/1/medline PY - 1995/1/1/entrez SP - 49 EP - 52 JF - Acta anaesthesiologica Scandinavica. Supplementum JO - Acta Anaesthesiol Scand Suppl VL - 107 N2 - Multi-wavelength photometers, blood gas analysers and pulse oximeters are widely used to measure various oxygen-related quantities. The definitions of these quantities are not always correct. This paper gives insight in the various definitions for oxygen quantities. Furthermore, the possible influences of dyshaemoglobins and fetal haemoglobin on the accuracy of pulse oximetry are discussed. As pulse oximeters are constructed for the determination of arterial oxygen saturation, they should be validated with sample oxygen saturation values and not with the oxyhaemoglobin fraction. The influence of carboxyhaemoglobin is insubstantial over an oxygen saturation range of 0% to 100%. Through the presence of methaemoglobin, pulse oximetry will give an underestimation above 70% and an overestimation below 70% oxygen saturation. The influence of fetal haemoglobin is insignificant in the neonatal use of pulse oximetry, in the range of 75% to 100% arterial oxygen saturation. However, a pulse oximeter underestimates the arterial oxygen saturation at the 25% level with 5%, if the pulse oximeter has been calibrated in human adults. Such a low level of arterial oxygen saturation can be present in the fetus during labor. SN - 0515-2720 UR - https://www.unboundmedicine.com/medline/citation/8599297/Notes_on_the_apparent_discordance_of_pulse_oximetry_and_multi_wavelength_haemoglobin_photometry_ DB - PRIME DP - Unbound Medicine ER -