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A simple quality control protocol for haemoximetry using standard p50.

Abstract

We have designed a quality control tool for haemoximetry using the principle that standard p50, calculated from blood gas and haemoximetry measurements using the Siggaard-Andersen algorithm, remains unchanged when a specimen of venous blood is oxygenated progressively to 97% saturation of haemoglobin. If the haemoximeter is inaccurate, progressively larger deviations of standard p50 from the constant value occur above 80% saturation. Deviations too small to be detected by analysis of quality control materials comprised of non-haemoglobin dyes and yet sufficient to cause significant errors in derived extractivity parameters can be detected by this method. The suggested protocol is easy to perform, and is recommended as a quality control tool for blood gas analyser/haemoximeters used to determine arterial extractivity parameters.

Authors+Show Affiliations

Royal Brisbane Hospital, Queensland, Australia.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8599299

Citation

Morgan, J, et al. "A Simple Quality Control Protocol for Haemoximetry Using Standard P50." Acta Anaesthesiologica Scandinavica. Supplementum, vol. 107, 1995, pp. 57-9.
Morgan J, Clague A, Rayfield J, et al. A simple quality control protocol for haemoximetry using standard p50. Acta Anaesthesiol Scand Suppl. 1995;107:57-9.
Morgan, J., Clague, A., Rayfield, J., & Endre, Z. (1995). A simple quality control protocol for haemoximetry using standard p50. Acta Anaesthesiologica Scandinavica. Supplementum, 107, 57-9.
Morgan J, et al. A Simple Quality Control Protocol for Haemoximetry Using Standard P50. Acta Anaesthesiol Scand Suppl. 1995;107:57-9. PubMed PMID: 8599299.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A simple quality control protocol for haemoximetry using standard p50. AU - Morgan,J, AU - Clague,A, AU - Rayfield,J, AU - Endre,Z, PY - 1995/1/1/pubmed PY - 1995/1/1/medline PY - 1995/1/1/entrez SP - 57 EP - 9 JF - Acta anaesthesiologica Scandinavica. Supplementum JO - Acta Anaesthesiol Scand Suppl VL - 107 N2 - We have designed a quality control tool for haemoximetry using the principle that standard p50, calculated from blood gas and haemoximetry measurements using the Siggaard-Andersen algorithm, remains unchanged when a specimen of venous blood is oxygenated progressively to 97% saturation of haemoglobin. If the haemoximeter is inaccurate, progressively larger deviations of standard p50 from the constant value occur above 80% saturation. Deviations too small to be detected by analysis of quality control materials comprised of non-haemoglobin dyes and yet sufficient to cause significant errors in derived extractivity parameters can be detected by this method. The suggested protocol is easy to perform, and is recommended as a quality control tool for blood gas analyser/haemoximeters used to determine arterial extractivity parameters. SN - 0515-2720 UR - https://www.unboundmedicine.com/medline/citation/8599299/A_simple_quality_control_protocol_for_haemoximetry_using_standard_p50_ L2 - https://antibodies.cancer.gov/detail/CPTC-CD40-1 DB - PRIME DP - Unbound Medicine ER -