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[Changes in insulin (IRI) and NEFA levels in diabetic subjects after acute intravenous glipizide and tolbutamide administration].
Arch Sci Med (Torino). 1977 Jan-Mar; 134(1):33-8.AS

Abstract

Glypizide and i.v. tolbutamide were administered to a series of diabetics. On different days, 10 subjects (controls for themselves) received 1 mg glypizide anal 100 mg tolbutamide; a further 10 received 2 mg glypizide and 200 mg tolbutamide. Blood sugar and insulin and NEFA values were determined every 10' for one hour after the injection. It was found that the hypoglycaemising activity of glypizide was about 140 times that of tolbutamide. It also caused a greater incretion of insuline and a more marked reduction of NEFA.

Authors

Fedeli S
No affiliation info available
Maglia A
No affiliation info available

MeSH

AgedAntigensDiabetes MellitusDrug EvaluationFatty Acids, NonesterifiedFemaleGlipizideHumansInsulinMaleMiddle AgedSulfonylurea CompoundsTolbutamide

Pub Type(s)

English Abstract
Journal Article

Language

ita

PubMed ID

860916

Citation

Fedeli, S, and A Maglia. "[Changes in Insulin (IRI) and NEFA Levels in Diabetic Subjects After Acute Intravenous Glipizide and Tolbutamide Administration]." Archivio Per Le Scienze Mediche, vol. 134, no. 1, 1977, pp. 33-8.
Fedeli S, Maglia A. [Changes in insulin (IRI) and NEFA levels in diabetic subjects after acute intravenous glipizide and tolbutamide administration]. Arch Sci Med (Torino). 1977;134(1):33-8.
Fedeli, S., & Maglia, A. (1977). [Changes in insulin (IRI) and NEFA levels in diabetic subjects after acute intravenous glipizide and tolbutamide administration]. Archivio Per Le Scienze Mediche, 134(1), 33-8.
Fedeli S, Maglia A. [Changes in Insulin (IRI) and NEFA Levels in Diabetic Subjects After Acute Intravenous Glipizide and Tolbutamide Administration]. Arch Sci Med (Torino). 1977 Jan-Mar;134(1):33-8. PubMed PMID: 860916.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Changes in insulin (IRI) and NEFA levels in diabetic subjects after acute intravenous glipizide and tolbutamide administration]. AU - Fedeli,S, AU - Maglia,A, PY - 1977/1/1/pubmed PY - 1977/1/1/medline PY - 1977/1/1/entrez SP - 33 EP - 8 JF - Archivio per le scienze mediche JO - Arch Sci Med (Torino) VL - 134 IS - 1 N2 - Glypizide and i.v. tolbutamide were administered to a series of diabetics. On different days, 10 subjects (controls for themselves) received 1 mg glypizide anal 100 mg tolbutamide; a further 10 received 2 mg glypizide and 200 mg tolbutamide. Blood sugar and insulin and NEFA values were determined every 10' for one hour after the injection. It was found that the hypoglycaemising activity of glypizide was about 140 times that of tolbutamide. It also caused a greater incretion of insuline and a more marked reduction of NEFA. SN - 0004-0312 UR - https://www.unboundmedicine.com/medline/citation/860916/[Changes_in_insulin__IRI__and_NEFA_levels_in_diabetic_subjects_after_acute_intravenous_glipizide_and_tolbutamide_administration]_ DB - PRIME DP - Unbound Medicine ER -