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Paraganglioma of the cauda equina. A case report and review of the literature.
APMIS. 1996 Mar; 104(3):234-40.A

Abstract

A 59-year-old man presented with clinical evidence of a primary tumor of the cauda equina region. It was well circumscribed and was completely removed by neurosurgery. Routine staining showed that it had structural similarities to an ependymoma, but immunohistochemistry with antisera to synaptophysin, NSE, chromogranin-A and PGP 9.5 proved it to be a neuroendocrine tumor, i.e. a paraganglioma. We propose the use of endocrine markers in cases with tumors of the cauda equina to differentiate a paraganglioma from an ependymoma. Paragangliomas appear to have a better clinical outcome than ependymomas. Recurrence after surgery for a paraganglioma in the cauda equina region, especially if it is encapsulated, is rarely encountered.

Authors+Show Affiliations

Department of Pathology, University Hospital, Uppsala, Sweden.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Review

Language

eng

PubMed ID

8611199

Citation

Bak, J, et al. "Paraganglioma of the Cauda Equina. a Case Report and Review of the Literature." APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica, vol. 104, no. 3, 1996, pp. 234-40.
Bak J, Olsson Y, Grimelius L, et al. Paraganglioma of the cauda equina. A case report and review of the literature. APMIS. 1996;104(3):234-40.
Bak, J., Olsson, Y., Grimelius, L., & Spännare, B. (1996). Paraganglioma of the cauda equina. A case report and review of the literature. APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica, 104(3), 234-40.
Bak J, et al. Paraganglioma of the Cauda Equina. a Case Report and Review of the Literature. APMIS. 1996;104(3):234-40. PubMed PMID: 8611199.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Paraganglioma of the cauda equina. A case report and review of the literature. AU - Bak,J, AU - Olsson,Y, AU - Grimelius,L, AU - Spännare,B, PY - 1996/3/1/pubmed PY - 1996/3/1/medline PY - 1996/3/1/entrez SP - 234 EP - 40 JF - APMIS : acta pathologica, microbiologica, et immunologica Scandinavica JO - APMIS VL - 104 IS - 3 N2 - A 59-year-old man presented with clinical evidence of a primary tumor of the cauda equina region. It was well circumscribed and was completely removed by neurosurgery. Routine staining showed that it had structural similarities to an ependymoma, but immunohistochemistry with antisera to synaptophysin, NSE, chromogranin-A and PGP 9.5 proved it to be a neuroendocrine tumor, i.e. a paraganglioma. We propose the use of endocrine markers in cases with tumors of the cauda equina to differentiate a paraganglioma from an ependymoma. Paragangliomas appear to have a better clinical outcome than ependymomas. Recurrence after surgery for a paraganglioma in the cauda equina region, especially if it is encapsulated, is rarely encountered. SN - 0903-4641 UR - https://www.unboundmedicine.com/medline/citation/8611199/Paraganglioma_of_the_cauda_equina__A_case_report_and_review_of_the_literature_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0903-4641&date=1996&volume=104&spage=234 DB - PRIME DP - Unbound Medicine ER -