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Etiology of rickets in Nigerian children.
J Pediatr. 1996 May; 128(5 Pt 1):692-4.JPed

Abstract

We studied 26 Nigerian children with active rickets (13 boys, 13 girls), aged 1 to 5 years, and compared results of biochemical studies with those of healthy control subjects. The plasma 1,25-dihydroxyvitamin D level was elevated (568 +/- 317 pmol/L) and the 25-hydroxyvitamin D level was (36 +/- 28 mol/L) in the children with rickets compared with the control subjects (369 +/- 134 nmol/L and 69 +/- 22 nmol/L, respectively). The results suggest that rickets in Nigeria is largely the result of calcium deficiency and that vitamin D deficiency and possibly end organ resistance may be contributory factors.

Authors+Show Affiliations

Department of Orthopaedics, Obafemi Awolowo University, Ile-Ife, Nigeria.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

8627444

Citation

Oginni, L M., et al. "Etiology of Rickets in Nigerian Children." The Journal of Pediatrics, vol. 128, no. 5 Pt 1, 1996, pp. 692-4.
Oginni LM, Worsfold M, Oyelami OA, et al. Etiology of rickets in Nigerian children. J Pediatr. 1996;128(5 Pt 1):692-4.
Oginni, L. M., Worsfold, M., Oyelami, O. A., Sharp, C. A., Powell, D. E., & Davie, M. W. (1996). Etiology of rickets in Nigerian children. The Journal of Pediatrics, 128(5 Pt 1), 692-4.
Oginni LM, et al. Etiology of Rickets in Nigerian Children. J Pediatr. 1996;128(5 Pt 1):692-4. PubMed PMID: 8627444.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Etiology of rickets in Nigerian children. AU - Oginni,L M, AU - Worsfold,M, AU - Oyelami,O A, AU - Sharp,C A, AU - Powell,D E, AU - Davie,M W, PY - 1996/5/1/pubmed PY - 1996/5/1/medline PY - 1996/5/1/entrez SP - 692 EP - 4 JF - The Journal of pediatrics JO - J. Pediatr. VL - 128 IS - 5 Pt 1 N2 - We studied 26 Nigerian children with active rickets (13 boys, 13 girls), aged 1 to 5 years, and compared results of biochemical studies with those of healthy control subjects. The plasma 1,25-dihydroxyvitamin D level was elevated (568 +/- 317 pmol/L) and the 25-hydroxyvitamin D level was (36 +/- 28 mol/L) in the children with rickets compared with the control subjects (369 +/- 134 nmol/L and 69 +/- 22 nmol/L, respectively). The results suggest that rickets in Nigeria is largely the result of calcium deficiency and that vitamin D deficiency and possibly end organ resistance may be contributory factors. SN - 0022-3476 UR - https://www.unboundmedicine.com/medline/citation/8627444/Etiology_of_rickets_in_Nigerian_children_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0022-3476(96)80137-5 DB - PRIME DP - Unbound Medicine ER -