Citation
Conter, V, et al. "High-dose Cytosine Arabinoside and Fractionated Total Body Irradiation as a Preparative Regimen for the Treatment of Children With Acute Lymphoblastic Leukemia and Down Syndrome By Allogeneic Bone Marrow Transplantation." Bone Marrow Transplantation, vol. 17, no. 2, 1996, pp. 287-9.
Conter V, D'Angelo P, Rizzari C, et al. High-dose cytosine arabinoside and fractionated total body irradiation as a preparative regimen for the treatment of children with acute lymphoblastic leukemia and Down syndrome by allogeneic bone marrow transplantation. Bone Marrow Transplant. 1996;17(2):287-9.
Conter, V., D'Angelo, P., Rizzari, C., Jankovic, M., Dampier, C., Masera, G., & Johnson, F. L. (1996). High-dose cytosine arabinoside and fractionated total body irradiation as a preparative regimen for the treatment of children with acute lymphoblastic leukemia and Down syndrome by allogeneic bone marrow transplantation. Bone Marrow Transplantation, 17(2), 287-9.
Conter V, et al. High-dose Cytosine Arabinoside and Fractionated Total Body Irradiation as a Preparative Regimen for the Treatment of Children With Acute Lymphoblastic Leukemia and Down Syndrome By Allogeneic Bone Marrow Transplantation. Bone Marrow Transplant. 1996;17(2):287-9. PubMed PMID: 8640182.
TY - JOUR
T1 - High-dose cytosine arabinoside and fractionated total body irradiation as a preparative regimen for the treatment of children with acute lymphoblastic leukemia and Down syndrome by allogeneic bone marrow transplantation.
AU - Conter,V,
AU - D'Angelo,P,
AU - Rizzari,C,
AU - Jankovic,M,
AU - Dampier,C,
AU - Masera,G,
AU - Johnson,F L,
PY - 1996/2/1/pubmed
PY - 1996/2/1/medline
PY - 1996/2/1/entrez
SP - 287
EP - 9
JF - Bone marrow transplantation
JO - Bone Marrow Transplant
VL - 17
IS - 2
N2 - The early toxicity, incidence of graft-versus-host disease (GVHD) and long-term follow-up were evaluated in two children with Down syndrome (DS) treated for acute lymphoblastic leukemia (ALL) in second complete remission by HLA-matched sibling allogeneic bone marrow transplantation (BMT). Preparative conditioning therapy consisted of cytosine arabinoside (Ara-C) and fractionated total body irradiation (F-TBI) and GVHD prophylaxis of cyclosporin A. The conditioning regimen was well tolerated, the only acute complication being mild mucositis. Engraftment (polymorphonuclear cells >500/microliter) was documented by day +17 in both patients. One child remains in continuous complete remission, without medical problems, 60 months after BMT. The second patient died from complications associated with chronic GVHD 21 months following BMT. Ara-C and F-TBI is a well-tolerated preparative regimen for children with DS undergoing allogeneic BMT.
SN - 0268-3369
UR - https://www.unboundmedicine.com/medline/citation/8640182/High_dose_cytosine_arabinoside_and_fractionated_total_body_irradiation_as_a_preparative_regimen_for_the_treatment_of_children_with_acute_lymphoblastic_leukemia_and_Down_syndrome_by_allogeneic_bone_marrow_transplantation_
L2 - http://www.diseaseinfosearch.org/result/188
DB - PRIME
DP - Unbound Medicine
ER -