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[Colonic perforation during combined steroid and radiotherapy. Diagnosis and treatment].
Tidsskr Nor Laegeforen. 1996 Feb 28; 116(6):731-2.TN

Abstract

Eight patients with colon perforations after combined treatment with radiotherapy and steroid medication are studied retrospectively. Sigmoid diverticuli perforated after a minimum of 5 days treatment. The main symptom was a varying degree of abdominal pain. Clinical parameters were of limited value. The most important single examination was plain abdominal x-ray, though this was not positive in all cases. Seven patients were operated on, one with simple suture, the rest with Hartmann's procedure. None developed postoperative peritonitis. One died from cerebral infarction. Four died within 38 days postoperatively after discharge from hospital. Abdominal symptoms during high dose steroid treatment may indicate perforation of the colon. Immediate operative intervention may have an uncomplicated postoperative course.

Authors+Show Affiliations

Wiig JN
Kirurgisk onkologisk avdeling, Det Norske Radiumhospital, Oslo.
Aass N
No affiliation info available
Karlsen KO
No affiliation info available
Giercksky KE
No affiliation info available

MeSH

AgedAntineoplastic Agents, HormonalColonic DiseasesCombined Modality TherapyDexamethasoneFemaleHumansIntestinal PerforationMaleMiddle AgedPrednisoneRadiation InjuriesRadiotherapy DosageRetrospective Studies

Pub Type(s)

English Abstract
Journal Article

Language

nor

PubMed ID

8644074

Citation

Wiig, J N., et al. "[Colonic Perforation During Combined Steroid and Radiotherapy. Diagnosis and Treatment]." Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke, vol. 116, no. 6, 1996, pp. 731-2.
Wiig JN, Aass N, Karlsen KO, et al. [Colonic perforation during combined steroid and radiotherapy. Diagnosis and treatment]. Tidsskr Nor Laegeforen. 1996;116(6):731-2.
Wiig, J. N., Aass, N., Karlsen, K. O., & Giercksky, K. E. (1996). [Colonic perforation during combined steroid and radiotherapy. Diagnosis and treatment]. Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke, 116(6), 731-2.
Wiig JN, et al. [Colonic Perforation During Combined Steroid and Radiotherapy. Diagnosis and Treatment]. Tidsskr Nor Laegeforen. 1996 Feb 28;116(6):731-2. PubMed PMID: 8644074.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Colonic perforation during combined steroid and radiotherapy. Diagnosis and treatment]. AU - Wiig,J N, AU - Aass,N, AU - Karlsen,K O, AU - Giercksky,K E, PY - 1996/2/28/pubmed PY - 1996/2/28/medline PY - 1996/2/28/entrez SP - 731 EP - 2 JF - Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke JO - Tidsskr Nor Laegeforen VL - 116 IS - 6 N2 - Eight patients with colon perforations after combined treatment with radiotherapy and steroid medication are studied retrospectively. Sigmoid diverticuli perforated after a minimum of 5 days treatment. The main symptom was a varying degree of abdominal pain. Clinical parameters were of limited value. The most important single examination was plain abdominal x-ray, though this was not positive in all cases. Seven patients were operated on, one with simple suture, the rest with Hartmann's procedure. None developed postoperative peritonitis. One died from cerebral infarction. Four died within 38 days postoperatively after discharge from hospital. Abdominal symptoms during high dose steroid treatment may indicate perforation of the colon. Immediate operative intervention may have an uncomplicated postoperative course. SN - 0029-2001 UR - https://www.unboundmedicine.com/medline/citation/8644074/[Colonic_perforation_during_combined_steroid_and_radiotherapy__Diagnosis_and_treatment]_ L2 - https://medlineplus.gov/colonicdiseases.html DB - PRIME DP - Unbound Medicine ER -