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Apolipoproteins AI and B and plasma lipid values in well-treated diabetic patients from Romania.
Rom J Intern Med. 1995 Jul-Dec; 33(3-4):249-56.RJ

Abstract

This review is aiming to study the values of apolipoprotein AI and B and plasma lipid levels (total cholesterol, HDL cholesterol, LDL cholesterol and triglyceride) in well-treated diabetic patients, and their possible relationship with hemoglobin A1, body mass index and insulin levels. The study groups were 26 insulin-dependent diabetic (IDDM) patients, 30 non-insulin-dependent diabetic (NIDDM) subjects and 20 non diabetic subjects (controls). Apolipoprotein AI concentrations were similar in the three groups, but apolipoprotein B values and apo B/apo AI ratio were significantly higher in IDDM as related to NIDDM patients (p < 0.001) and to non-diabetic subjects (p < 0.001). We were not able to find significant differences concerning plasma lipid values between the three groups. We found a weak correlation between apo B and hemoglobin AI in IDDM (r = 0.45; 0.02 < p < 0.05), but not in NIDDM patients. Body mass index was not related to the values of apolipoproteins AI and B. We found a positive but weak correlation between insulin levels and triglyceride (r = 0.42), and an inverse one with HDL cholesterol (r = 0.57; 0.02 < p < 0.05) in non-diabetic subjects only, while in NIDDM patients these associations were even less significant. Plasma insulin values strongly correlate to body mass index in both NIDDM (r = 0.64; p < 0.001) and in control subjects (r = 0.73; 0.001 < p < 0.001).

Authors+Show Affiliations

Dabelea D
County Hospital, University of Medicine and Pharmacy, Timişoara, Romania.
Serban V
No affiliation info available
Băcanu G
No affiliation info available
Deutsch G
No affiliation info available
Pataki C
No affiliation info available
Dan I
No affiliation info available

MeSH

AdultApolipoprotein A-IApolipoproteins BBody Mass IndexDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2FemaleGlycated Hemoglobin AHumansInsulinLinear ModelsLipidsMaleMiddle AgedRomania

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

8646198

Citation

Dabelea, D, et al. "Apolipoproteins AI and B and Plasma Lipid Values in Well-treated Diabetic Patients From Romania." Romanian Journal of Internal Medicine = Revue Roumaine De Medecine Interne, vol. 33, no. 3-4, 1995, pp. 249-56.
Dabelea D, Serban V, Băcanu G, et al. Apolipoproteins AI and B and plasma lipid values in well-treated diabetic patients from Romania. Rom J Intern Med. 1995;33(3-4):249-56.
Dabelea, D., Serban, V., Băcanu, G., Deutsch, G., Pataki, C., & Dan, I. (1995). Apolipoproteins AI and B and plasma lipid values in well-treated diabetic patients from Romania. Romanian Journal of Internal Medicine = Revue Roumaine De Medecine Interne, 33(3-4), 249-56.
Dabelea D, et al. Apolipoproteins AI and B and Plasma Lipid Values in Well-treated Diabetic Patients From Romania. Rom J Intern Med. 1995 Jul-Dec;33(3-4):249-56. PubMed PMID: 8646198.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Apolipoproteins AI and B and plasma lipid values in well-treated diabetic patients from Romania. AU - Dabelea,D, AU - Serban,V, AU - Băcanu,G, AU - Deutsch,G, AU - Pataki,C, AU - Dan,I, PY - 1995/7/1/pubmed PY - 1995/7/1/medline PY - 1995/7/1/entrez SP - 249 EP - 56 JF - Romanian journal of internal medicine = Revue roumaine de medecine interne JO - Rom J Intern Med VL - 33 IS - 3-4 N2 - This review is aiming to study the values of apolipoprotein AI and B and plasma lipid levels (total cholesterol, HDL cholesterol, LDL cholesterol and triglyceride) in well-treated diabetic patients, and their possible relationship with hemoglobin A1, body mass index and insulin levels. The study groups were 26 insulin-dependent diabetic (IDDM) patients, 30 non-insulin-dependent diabetic (NIDDM) subjects and 20 non diabetic subjects (controls). Apolipoprotein AI concentrations were similar in the three groups, but apolipoprotein B values and apo B/apo AI ratio were significantly higher in IDDM as related to NIDDM patients (p < 0.001) and to non-diabetic subjects (p < 0.001). We were not able to find significant differences concerning plasma lipid values between the three groups. We found a weak correlation between apo B and hemoglobin AI in IDDM (r = 0.45; 0.02 < p < 0.05), but not in NIDDM patients. Body mass index was not related to the values of apolipoproteins AI and B. We found a positive but weak correlation between insulin levels and triglyceride (r = 0.42), and an inverse one with HDL cholesterol (r = 0.57; 0.02 < p < 0.05) in non-diabetic subjects only, while in NIDDM patients these associations were even less significant. Plasma insulin values strongly correlate to body mass index in both NIDDM (r = 0.64; p < 0.001) and in control subjects (r = 0.73; 0.001 < p < 0.001). SN - 1220-4749 UR - https://www.unboundmedicine.com/medline/citation/8646198/Apolipoproteins_AI_and_B_and_plasma_lipid_values_in_well_treated_diabetic_patients_from_Romania_ DB - PRIME DP - Unbound Medicine ER -