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Microvascular invasion of the seminal vesicles in adenocarcinoma of the prostate.
Prostate. 1996 Jun; 28(6):359-63.P

Abstract

The objective of this article is to determine the relationship between microvascular invasion and seminal vesicle invasion in prostatic adenocarcinoma. Radical prostatectomies with seminal vesicle involvement were examined histologically and immunohistochemically with antibodies directed against S-100 protein and factor VIII. Microvascular invasion of the seminal vesicles showed a positive correlation with microvascular and capsular invasion of the prostate (P = 0.006 and 0.048, respectively) and lymph node metastases. Tumor progression was found in 8 of 14 (57%) patients with microvascular invasion of the seminal vesicles, compared with 3 of 22 (14%) without microvascular invasion (P = 0.001). Microvascular invasion of the seminal vesicles is predictive of tumor progression and lymph node metastases in prostatic adenocarcinoma.

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Authors+Show Affiliations

Graham SD
Department of Surgery, Emory University School of Medicine, Atlanta, Georgia, USA.
Napalkov P
No affiliation info available
Watts L
No affiliation info available
Salomao D
No affiliation info available
Bostwick DG
No affiliation info available

MeSH

AdenocarcinomaFactor VIIIHumansImmunohistochemistryLymph NodesLymphatic MetastasisMaleMicrocirculationNeoplasm InvasivenessProstateProstatectomyProstatic NeoplasmsS100 ProteinsSeminal Vesicles

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8650072

Citation

Graham, S D., et al. "Microvascular Invasion of the Seminal Vesicles in Adenocarcinoma of the Prostate." The Prostate, vol. 28, no. 6, 1996, pp. 359-63.
Graham SD, Napalkov P, Watts L, et al. Microvascular invasion of the seminal vesicles in adenocarcinoma of the prostate. Prostate. 1996;28(6):359-63.
Graham, S. D., Napalkov, P., Watts, L., Salomao, D., & Bostwick, D. G. (1996). Microvascular invasion of the seminal vesicles in adenocarcinoma of the prostate. The Prostate, 28(6), 359-63.
Graham SD, et al. Microvascular Invasion of the Seminal Vesicles in Adenocarcinoma of the Prostate. Prostate. 1996;28(6):359-63. PubMed PMID: 8650072.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Microvascular invasion of the seminal vesicles in adenocarcinoma of the prostate. AU - Graham,S D,Jr AU - Napalkov,P, AU - Watts,L, AU - Salomao,D, AU - Bostwick,D G, PY - 1996/6/1/pubmed PY - 2000/6/20/medline PY - 1996/6/1/entrez SP - 359 EP - 63 JF - The Prostate JO - Prostate VL - 28 IS - 6 N2 - The objective of this article is to determine the relationship between microvascular invasion and seminal vesicle invasion in prostatic adenocarcinoma. Radical prostatectomies with seminal vesicle involvement were examined histologically and immunohistochemically with antibodies directed against S-100 protein and factor VIII. Microvascular invasion of the seminal vesicles showed a positive correlation with microvascular and capsular invasion of the prostate (P = 0.006 and 0.048, respectively) and lymph node metastases. Tumor progression was found in 8 of 14 (57%) patients with microvascular invasion of the seminal vesicles, compared with 3 of 22 (14%) without microvascular invasion (P = 0.001). Microvascular invasion of the seminal vesicles is predictive of tumor progression and lymph node metastases in prostatic adenocarcinoma. SN - 0270-4137 UR - https://www.unboundmedicine.com/medline/citation/8650072/Microvascular_invasion_of_the_seminal_vesicles_in_adenocarcinoma_of_the_prostate_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0270-4137&date=1996&volume=28&issue=6&spage=359 DB - PRIME DP - Unbound Medicine ER -