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Combined use of leg scanning and impedance plethysmography in suspected venous thrombosis. An alternative to venography.
N Engl J Med. 1977 Jun 30; 296(26):1497-500.NEJM

Abstract

Venography is the standard method for the diagnosis of venous thrombosis but is invasive and may cause discomfort. We evaluated the combination of impedance plethysmography and 125I-fibrinogen leg scanning as an alternative to venography in 200 symptomatic patients. One or both of these less invasive tests was positive in 81 of 86 patients with positive venograms (sensitivity of 94 per cent) and both were negative in 104 of 114 patients with negative venograms (specificity of 91 per cent). These two tests detected all 60 patients with popliteal or more proximal venous thrombosis and 21 of 26 patients with calf-vein thrombosis. In addition, this approach detected 21 of 22 patients with calf-vein thrombosis with symptoms for eight days or less. These results suggest that the combination of these two less invasive tests can be used as an alternative to venography in selected patients with clinically suspected venous thrombosis.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

865529

Citation

Hull, R, et al. "Combined Use of Leg Scanning and Impedance Plethysmography in Suspected Venous Thrombosis. an Alternative to Venography." The New England Journal of Medicine, vol. 296, no. 26, 1977, pp. 1497-500.
Hull R, Hirsh J, Sackett DL, et al. Combined use of leg scanning and impedance plethysmography in suspected venous thrombosis. An alternative to venography. N Engl J Med. 1977;296(26):1497-500.
Hull, R., Hirsh, J., Sackett, D. L., Powers, P., Turpie, A. G., & Walker, I. (1977). Combined use of leg scanning and impedance plethysmography in suspected venous thrombosis. An alternative to venography. The New England Journal of Medicine, 296(26), 1497-500.
Hull R, et al. Combined Use of Leg Scanning and Impedance Plethysmography in Suspected Venous Thrombosis. an Alternative to Venography. N Engl J Med. 1977 Jun 30;296(26):1497-500. PubMed PMID: 865529.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Combined use of leg scanning and impedance plethysmography in suspected venous thrombosis. An alternative to venography. AU - Hull,R, AU - Hirsh,J, AU - Sackett,D L, AU - Powers,P, AU - Turpie,A G, AU - Walker,I, PY - 1977/6/30/pubmed PY - 1977/6/30/medline PY - 1977/6/30/entrez SP - 1497 EP - 500 JF - The New England journal of medicine JO - N Engl J Med VL - 296 IS - 26 N2 - Venography is the standard method for the diagnosis of venous thrombosis but is invasive and may cause discomfort. We evaluated the combination of impedance plethysmography and 125I-fibrinogen leg scanning as an alternative to venography in 200 symptomatic patients. One or both of these less invasive tests was positive in 81 of 86 patients with positive venograms (sensitivity of 94 per cent) and both were negative in 104 of 114 patients with negative venograms (specificity of 91 per cent). These two tests detected all 60 patients with popliteal or more proximal venous thrombosis and 21 of 26 patients with calf-vein thrombosis. In addition, this approach detected 21 of 22 patients with calf-vein thrombosis with symptoms for eight days or less. These results suggest that the combination of these two less invasive tests can be used as an alternative to venography in selected patients with clinically suspected venous thrombosis. SN - 0028-4793 UR - https://www.unboundmedicine.com/medline/citation/865529/Combined_use_of_leg_scanning_and_impedance_plethysmography_in_suspected_venous_thrombosis__An_alternative_to_venography_ L2 - https://www.nejm.org/doi/10.1056/NEJM197706302962604?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -