Tags

Type your tag names separated by a space and hit enter

Physical activity, waist-to-hip ratio, and other risk factors for ovarian cancer: a follow-up study of older women.
Epidemiology 1996; 7(1):38-45E

Abstract

We investigated the association of epithelial ovarian cancer with physical activity, waist-to-hip ratio, reproductive factors, and family history of cancer in a prospective cohort study of 31,396 postmenopausal women. Ninety-seven women developed incident epithelial ovarian cancer over 7 years. The number of livebirths was associated with lower risk (multivariate-adjusted relative risks for 1-2, 3-4, and > 4 livebirths compared with nulliparity were 0.64, 0.47, and 0.43, respectively). A family history of ovarian cancer in a first-degree relative was associated with a 2.5 times greater risk (95% confidence interval = 0.90-6.7). Multivariate-adjusted relative risks for the upper three quartiles of waist-to-hip ratio compared with the lowest quartile were 2.0, 1.6, and 2.3, respectively. Women with "moderate" and "high" levels of physical activity compared with those with "low" physical activity had relative risks of 1.4 and 2.1, respectively. Positive associations of physical activity and waist-to-hip ratio with ovarian cancer seem inconsistent with existing theories of ovarian cancer pathogenesis.

Authors+Show Affiliations

School of Public Health, University of Minnesota, MN 55454-1015, USA.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

8664399

Citation

Mink, P J., et al. "Physical Activity, Waist-to-hip Ratio, and Other Risk Factors for Ovarian Cancer: a Follow-up Study of Older Women." Epidemiology (Cambridge, Mass.), vol. 7, no. 1, 1996, pp. 38-45.
Mink PJ, Folsom AR, Sellers TA, et al. Physical activity, waist-to-hip ratio, and other risk factors for ovarian cancer: a follow-up study of older women. Epidemiology. 1996;7(1):38-45.
Mink, P. J., Folsom, A. R., Sellers, T. A., & Kushi, L. H. (1996). Physical activity, waist-to-hip ratio, and other risk factors for ovarian cancer: a follow-up study of older women. Epidemiology (Cambridge, Mass.), 7(1), pp. 38-45.
Mink PJ, et al. Physical Activity, Waist-to-hip Ratio, and Other Risk Factors for Ovarian Cancer: a Follow-up Study of Older Women. Epidemiology. 1996;7(1):38-45. PubMed PMID: 8664399.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Physical activity, waist-to-hip ratio, and other risk factors for ovarian cancer: a follow-up study of older women. AU - Mink,P J, AU - Folsom,A R, AU - Sellers,T A, AU - Kushi,L H, PY - 1996/1/1/pubmed PY - 1996/1/1/medline PY - 1996/1/1/entrez SP - 38 EP - 45 JF - Epidemiology (Cambridge, Mass.) JO - Epidemiology VL - 7 IS - 1 N2 - We investigated the association of epithelial ovarian cancer with physical activity, waist-to-hip ratio, reproductive factors, and family history of cancer in a prospective cohort study of 31,396 postmenopausal women. Ninety-seven women developed incident epithelial ovarian cancer over 7 years. The number of livebirths was associated with lower risk (multivariate-adjusted relative risks for 1-2, 3-4, and > 4 livebirths compared with nulliparity were 0.64, 0.47, and 0.43, respectively). A family history of ovarian cancer in a first-degree relative was associated with a 2.5 times greater risk (95% confidence interval = 0.90-6.7). Multivariate-adjusted relative risks for the upper three quartiles of waist-to-hip ratio compared with the lowest quartile were 2.0, 1.6, and 2.3, respectively. Women with "moderate" and "high" levels of physical activity compared with those with "low" physical activity had relative risks of 1.4 and 2.1, respectively. Positive associations of physical activity and waist-to-hip ratio with ovarian cancer seem inconsistent with existing theories of ovarian cancer pathogenesis. SN - 1044-3983 UR - https://www.unboundmedicine.com/medline/citation/8664399/Physical_activity_waist_to_hip_ratio_and_other_risk_factors_for_ovarian_cancer:_a_follow_up_study_of_older_women_ L2 - http://dx.doi.org/10.1097/00001648-199601000-00008 DB - PRIME DP - Unbound Medicine ER -