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[Transjugular placement of an intrahepatic portosystemic shunt as current treatment for complications of portal hypertension].
Ned Tijdschr Geneeskd. 1996 Mar 23; 140(12):659-64.NT

Abstract

OBJECTIVE

To analyse the results in 31 patients who underwent transjugular intrahepatic portosystemic shunting (TIPS).

DESIGN

Retrospective study.

SETTING

University Hospital Rotterdam-Dijkzigt, Rotterdam, the Netherlands.

METHOD

Data of all patients who underwent a TIPS procedure from February 1992 to September 1994 were analysed. Indications for TIPS included recurrent variceal bleedings and refractory ascites. TIPS was performed under general anaesthesia. After TIPS heparin was given during one week.

RESULTS

TIPS creation succeeded in 29 out of 31 patients. The mean portosystemic pressure gradient after TIPS was 9.6 mmHg. After 1.5 years the cumulative percentage of recurrent variceal bleeding was 44. The quantity of ascites decreased in 73% of the patients. During recatheterisation shunt dysfunction was seen in 16 out of 21 patients. Mortality was 13% within 30 days. The actuarial percentage of patients who died was 43 after 1.5 years. Mortality depended on Child-Pugh classification.

CONCLUSION

TIPS is a new, safe and fast treatment for patients with complications of portal hypertension. The number of recurrent variceal bleedings was substantial. Intensive control examinations are imperative to discern shunt dysfunction. Long-term survival rates and morbidity depend on the seriousness of the pre-existing liver disease.

Authors+Show Affiliations

Buiskool RA
Afd. Radiodiagnostiek, Academisch Ziekenhuis Rotterdam-Dijkzigt.
Pieterman H
No affiliation info available
van Buuren HR
No affiliation info available
Laméris JS
No affiliation info available

MeSH

AdultAgedAngioplasty, BalloonAscitesEsophageal and Gastric VaricesFemaleGastrointestinal HemorrhageHepatic EncephalopathyHepatic VeinsHumansHypertension, PortalJugular VeinsMaleMiddle AgedPortal VeinPortasystemic Shunt, SurgicalPostoperative ComplicationsRecurrenceRetrospective StudiesStents

Pub Type(s)

English Abstract
Journal Article

Language

dut

PubMed ID

8668239

Citation

Buiskool, R A., et al. "[Transjugular Placement of an Intrahepatic Portosystemic Shunt as Current Treatment for Complications of Portal Hypertension]." Nederlands Tijdschrift Voor Geneeskunde, vol. 140, no. 12, 1996, pp. 659-64.
Buiskool RA, Pieterman H, van Buuren HR, et al. [Transjugular placement of an intrahepatic portosystemic shunt as current treatment for complications of portal hypertension]. Ned Tijdschr Geneeskd. 1996;140(12):659-64.
Buiskool, R. A., Pieterman, H., van Buuren, H. R., & Laméris, J. S. (1996). [Transjugular placement of an intrahepatic portosystemic shunt as current treatment for complications of portal hypertension]. Nederlands Tijdschrift Voor Geneeskunde, 140(12), 659-64.
Buiskool RA, et al. [Transjugular Placement of an Intrahepatic Portosystemic Shunt as Current Treatment for Complications of Portal Hypertension]. Ned Tijdschr Geneeskd. 1996 Mar 23;140(12):659-64. PubMed PMID: 8668239.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Transjugular placement of an intrahepatic portosystemic shunt as current treatment for complications of portal hypertension]. AU - Buiskool,R A, AU - Pieterman,H, AU - van Buuren,H R, AU - Laméris,J S, PY - 1996/3/23/pubmed PY - 1996/3/23/medline PY - 1996/3/23/entrez SP - 659 EP - 64 JF - Nederlands tijdschrift voor geneeskunde JO - Ned Tijdschr Geneeskd VL - 140 IS - 12 N2 - OBJECTIVE: To analyse the results in 31 patients who underwent transjugular intrahepatic portosystemic shunting (TIPS). DESIGN: Retrospective study. SETTING: University Hospital Rotterdam-Dijkzigt, Rotterdam, the Netherlands. METHOD: Data of all patients who underwent a TIPS procedure from February 1992 to September 1994 were analysed. Indications for TIPS included recurrent variceal bleedings and refractory ascites. TIPS was performed under general anaesthesia. After TIPS heparin was given during one week. RESULTS: TIPS creation succeeded in 29 out of 31 patients. The mean portosystemic pressure gradient after TIPS was 9.6 mmHg. After 1.5 years the cumulative percentage of recurrent variceal bleeding was 44. The quantity of ascites decreased in 73% of the patients. During recatheterisation shunt dysfunction was seen in 16 out of 21 patients. Mortality was 13% within 30 days. The actuarial percentage of patients who died was 43 after 1.5 years. Mortality depended on Child-Pugh classification. CONCLUSION: TIPS is a new, safe and fast treatment for patients with complications of portal hypertension. The number of recurrent variceal bleedings was substantial. Intensive control examinations are imperative to discern shunt dysfunction. Long-term survival rates and morbidity depend on the seriousness of the pre-existing liver disease. SN - 0028-2162 UR - https://www.unboundmedicine.com/medline/citation/8668239/[Transjugular_placement_of_an_intrahepatic_portosystemic_shunt_as_current_treatment_for_complications_of_portal_hypertension]_ L2 - http://www.diseaseinfosearch.org/result/5881 DB - PRIME DP - Unbound Medicine ER -