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Multimodal evoked potentials in Alzheimer's disease and Binswanger's disease.
J Geriatr Psychiatry Neurol. 1996 Jan; 9(1):7-12.JG

Abstract

Somatosensory evoked potentials (SEPs), brainstem auditory evoked potentials (BAEPs), visual evoked potentials (VEPs), and auditory event-related potentials (ERPs) were studied in 15 patients with Alzheimer's disease (AD), eight patients with Binswanger's disease (BD), and 15 normal subjects. Patients with BD showed significant prolongation of the interpeak latency between N13 and N20 (N13-N20) and N20-P40 of SEPs as compared with the normal controls, whereas patients with AD only demonstrated significant prolongation of N20-P40. The interpeak latency between waves I and V of BAEPs in patients with both AD and BD was significantly longer than that of controls. There were no significant differences in P100 latency of VEPs among these three groups. Both groups with dementia showed significant prolongation of N200 and P300 latencies of ERPs compared with normal controls. In addition, patients with AD showed significant prolongation of P200 latency. We conclude that these two dementing diseases have different electrophysiologic features that may be related to their underlying pathogenetic mechanisms. Furthermore, the measurement of multimodal evoked potentials may be helpful in the differential diagnosis of AD and BD.

Authors+Show Affiliations

Fifth Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8679063

Citation

Tachibana, H, et al. "Multimodal Evoked Potentials in Alzheimer's Disease and Binswanger's Disease." Journal of Geriatric Psychiatry and Neurology, vol. 9, no. 1, 1996, pp. 7-12.
Tachibana H, Takeda M, Okuda B, et al. Multimodal evoked potentials in Alzheimer's disease and Binswanger's disease. J Geriatr Psychiatry Neurol. 1996;9(1):7-12.
Tachibana, H., Takeda, M., Okuda, B., Kawabata, K., Nishimura, H., Kodama, N., Iwamoto, Y., & Sugita, M. (1996). Multimodal evoked potentials in Alzheimer's disease and Binswanger's disease. Journal of Geriatric Psychiatry and Neurology, 9(1), 7-12.
Tachibana H, et al. Multimodal Evoked Potentials in Alzheimer's Disease and Binswanger's Disease. J Geriatr Psychiatry Neurol. 1996;9(1):7-12. PubMed PMID: 8679063.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Multimodal evoked potentials in Alzheimer's disease and Binswanger's disease. AU - Tachibana,H, AU - Takeda,M, AU - Okuda,B, AU - Kawabata,K, AU - Nishimura,H, AU - Kodama,N, AU - Iwamoto,Y, AU - Sugita,M, PY - 1996/1/1/pubmed PY - 1996/1/1/medline PY - 1996/1/1/entrez SP - 7 EP - 12 JF - Journal of geriatric psychiatry and neurology JO - J Geriatr Psychiatry Neurol VL - 9 IS - 1 N2 - Somatosensory evoked potentials (SEPs), brainstem auditory evoked potentials (BAEPs), visual evoked potentials (VEPs), and auditory event-related potentials (ERPs) were studied in 15 patients with Alzheimer's disease (AD), eight patients with Binswanger's disease (BD), and 15 normal subjects. Patients with BD showed significant prolongation of the interpeak latency between N13 and N20 (N13-N20) and N20-P40 of SEPs as compared with the normal controls, whereas patients with AD only demonstrated significant prolongation of N20-P40. The interpeak latency between waves I and V of BAEPs in patients with both AD and BD was significantly longer than that of controls. There were no significant differences in P100 latency of VEPs among these three groups. Both groups with dementia showed significant prolongation of N200 and P300 latencies of ERPs compared with normal controls. In addition, patients with AD showed significant prolongation of P200 latency. We conclude that these two dementing diseases have different electrophysiologic features that may be related to their underlying pathogenetic mechanisms. Furthermore, the measurement of multimodal evoked potentials may be helpful in the differential diagnosis of AD and BD. SN - 0891-9887 UR - https://www.unboundmedicine.com/medline/citation/8679063/Multimodal_evoked_potentials_in_Alzheimer's_disease_and_Binswanger's_disease_ L2 - https://journals.sagepub.com/doi/10.1177/089198879600900102?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -