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Parvovirus B19 infection in Behçet's disease.
Clin Exp Rheumatol. 1996 Jan-Feb; 14(1):71-3.CE

Abstract

OBJECTIVE

To investigate whether parvovirus B19 infection is associated with Behçet's disease (BD).

METHODS

Serum samples from 41 patients with BD and from 40 age- and sex-matched controls were studied. An ELISA assay was used to detect antibodies against parvovirus B19.

RESULTS

Six patients with BD (15.7%) had anti-B19 IgM antibodies in their serum samples indicating a recent infection, while no positivity for IgM antibodies was detected in the control group (p = 0.03).

CONCLUSION

Although there have been several reports of B19 infection associated with vasculitis, our findings do not strongly support the involvement of B19 in the pathogenesis of BD. The serological evidence of acute infection in 6 BD patients may be purely coincidental. There was also no positive correlation with the articular and vascular manifestations of BD.

Authors+Show Affiliations

Division of Rheumatology, Hacettepe University Medical School, Ankara, Turkey.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8697661

Citation

Kiraz, S, et al. "Parvovirus B19 Infection in Behçet's Disease." Clinical and Experimental Rheumatology, vol. 14, no. 1, 1996, pp. 71-3.
Kiraz S, Ertenli I, Benekli M, et al. Parvovirus B19 infection in Behçet's disease. Clin Exp Rheumatol. 1996;14(1):71-3.
Kiraz, S., Ertenli, I., Benekli, M., & Calgüneri, M. (1996). Parvovirus B19 infection in Behçet's disease. Clinical and Experimental Rheumatology, 14(1), 71-3.
Kiraz S, et al. Parvovirus B19 Infection in Behçet's Disease. Clin Exp Rheumatol. 1996 Jan-Feb;14(1):71-3. PubMed PMID: 8697661.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Parvovirus B19 infection in Behçet's disease. AU - Kiraz,S, AU - Ertenli,I, AU - Benekli,M, AU - Calgüneri,M, PY - 1996/1/1/pubmed PY - 1996/1/1/medline PY - 1996/1/1/entrez SP - 71 EP - 3 JF - Clinical and experimental rheumatology JO - Clin Exp Rheumatol VL - 14 IS - 1 N2 - OBJECTIVE: To investigate whether parvovirus B19 infection is associated with Behçet's disease (BD). METHODS: Serum samples from 41 patients with BD and from 40 age- and sex-matched controls were studied. An ELISA assay was used to detect antibodies against parvovirus B19. RESULTS: Six patients with BD (15.7%) had anti-B19 IgM antibodies in their serum samples indicating a recent infection, while no positivity for IgM antibodies was detected in the control group (p = 0.03). CONCLUSION: Although there have been several reports of B19 infection associated with vasculitis, our findings do not strongly support the involvement of B19 in the pathogenesis of BD. The serological evidence of acute infection in 6 BD patients may be purely coincidental. There was also no positive correlation with the articular and vascular manifestations of BD. SN - 0392-856X UR - https://www.unboundmedicine.com/medline/citation/8697661/Parvovirus_B19_infection_in_Behçet's_disease_ L2 - http://www.diseaseinfosearch.org/result/780 DB - PRIME DP - Unbound Medicine ER -