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Sucrase-isomaltase deficiency: changing pattern over two decades.
J Pediatr Gastroenterol Nutr. 1996 Apr; 22(3):284-8.JP

Abstract

Twenty-two cases of sucrase-isomaltase deficiency (SID) were observed over a period of 20 years. Since 1977 delay of introduction of sucrose and its decrease in infants' diets have modified the symptomatology. In general, onset of diarrhea has not taken place immediately but 15 days to 2 months after introduction of sucrose. Out of 12 cases with dehydration, five occurred 3 to 7 months after the beginning of sucrose diet. Hypotrophy was not constant (11 of 22 cases), thus diagnosis was delayed in 17 of 22 cases. A yellow complexion due to rising carotene levels in the blood is a striking feature. Because of falsely positive sucrose load tests (four out of 14 nonSID infants) and failure of the hydrogene breath test (one out of five studied cases), disaccharidase determination remains the key to diagnosis. Despite the genetic difference symptoms seem to depend on infant feeding practices.

Authors+Show Affiliations

Centre de Pediatrie Edmond-Lesne, Hôpital Trousseau, Paris, France.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8708882

Citation

Baudon, J J., et al. "Sucrase-isomaltase Deficiency: Changing Pattern Over Two Decades." Journal of Pediatric Gastroenterology and Nutrition, vol. 22, no. 3, 1996, pp. 284-8.
Baudon JJ, Veinberg F, Thioulouse E, et al. Sucrase-isomaltase deficiency: changing pattern over two decades. J Pediatr Gastroenterol Nutr. 1996;22(3):284-8.
Baudon, J. J., Veinberg, F., Thioulouse, E., Morgant, G., Aymard, P., & Charritat, J. L. (1996). Sucrase-isomaltase deficiency: changing pattern over two decades. Journal of Pediatric Gastroenterology and Nutrition, 22(3), 284-8.
Baudon JJ, et al. Sucrase-isomaltase Deficiency: Changing Pattern Over Two Decades. J Pediatr Gastroenterol Nutr. 1996;22(3):284-8. PubMed PMID: 8708882.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Sucrase-isomaltase deficiency: changing pattern over two decades. AU - Baudon,J J, AU - Veinberg,F, AU - Thioulouse,E, AU - Morgant,G, AU - Aymard,P, AU - Charritat,J L, PY - 1996/4/1/pubmed PY - 1996/4/1/medline PY - 1996/4/1/entrez SP - 284 EP - 8 JF - Journal of pediatric gastroenterology and nutrition JO - J. Pediatr. Gastroenterol. Nutr. VL - 22 IS - 3 N2 - Twenty-two cases of sucrase-isomaltase deficiency (SID) were observed over a period of 20 years. Since 1977 delay of introduction of sucrose and its decrease in infants' diets have modified the symptomatology. In general, onset of diarrhea has not taken place immediately but 15 days to 2 months after introduction of sucrose. Out of 12 cases with dehydration, five occurred 3 to 7 months after the beginning of sucrose diet. Hypotrophy was not constant (11 of 22 cases), thus diagnosis was delayed in 17 of 22 cases. A yellow complexion due to rising carotene levels in the blood is a striking feature. Because of falsely positive sucrose load tests (four out of 14 nonSID infants) and failure of the hydrogene breath test (one out of five studied cases), disaccharidase determination remains the key to diagnosis. Despite the genetic difference symptoms seem to depend on infant feeding practices. SN - 0277-2116 UR - https://www.unboundmedicine.com/medline/citation/8708882/Sucrase_isomaltase_deficiency:_changing_pattern_over_two_decades_ L2 - http://dx.doi.org/10.1097/00005176-199604000-00010 DB - PRIME DP - Unbound Medicine ER -