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Prenatal lead exposure and the pregnancy outcome. A case-control study in southern Poland.
Przegl Lek. 1996; 53(4):342-7.PL

Abstract

In an attempt to test null hypothesis (Ho): that prenatal lead exposure does not increase the risk of prematurity and the delivery of SGA infants, a case-control study was performed in four hospitals of Southern Poland (Kraków, Rabka, Limanowa, Zakopane). Lead content was determined in maternal and cord blood as well as in head and pubic hair by the GF AAS (Perkin Elmer). A significant interregional variation of lead content in maternal blood was observed. Lead concentration in maternal and cord blood was significantly higher in the group of mothers of SGA newborns when compared to the controls. This was not the case with respect to the mothers of preterm infants. Also, the comparison of lead concentration in head and pubic hair revealed no statistically significant case-control differences. For a combined population of cases and controls, a significant gradient of lead concentration between maternal and cord blood was demonstrated. The correlation between lead content in different body compartments was observed.

Conclusions.

Different blood lead levels observed in mothers from four hospitals suggest different exposure. Higher lead concentration in maternal blood was associated with an increased risk of the delivery of SGA infant.

Authors+Show Affiliations

I Klinika Chorób Dzieci, Polsko-Amerykańskiego Instytutu, Pediatrii Collegium Medicum Uniwersytetu Jagiellońskiego w Krakowie.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8711188

Citation

Pietrzyk, J J., et al. "Prenatal Lead Exposure and the Pregnancy Outcome. a Case-control Study in Southern Poland." Przeglad Lekarski, vol. 53, no. 4, 1996, pp. 342-7.
Pietrzyk JJ, Nowak A, Mitkowska Z, et al. Prenatal lead exposure and the pregnancy outcome. A case-control study in southern Poland. Przegl Lek. 1996;53(4):342-7.
Pietrzyk, J. J., Nowak, A., Mitkowska, Z., Zachwieja, Z., Chłopicka, J., Krośniak, M., Glińska, A., Strzelecki, T., Dobosz, P., Wrzosek, W., & Czarnowieska, A. (1996). Prenatal lead exposure and the pregnancy outcome. A case-control study in southern Poland. Przeglad Lekarski, 53(4), 342-7.
Pietrzyk JJ, et al. Prenatal Lead Exposure and the Pregnancy Outcome. a Case-control Study in Southern Poland. Przegl Lek. 1996;53(4):342-7. PubMed PMID: 8711188.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prenatal lead exposure and the pregnancy outcome. A case-control study in southern Poland. AU - Pietrzyk,J J, AU - Nowak,A, AU - Mitkowska,Z, AU - Zachwieja,Z, AU - Chłopicka,J, AU - Krośniak,M, AU - Glińska,A, AU - Strzelecki,T, AU - Dobosz,P, AU - Wrzosek,W, AU - Czarnowieska,A, PY - 1996/1/1/pubmed PY - 1996/1/1/medline PY - 1996/1/1/entrez SP - 342 EP - 7 JF - Przeglad lekarski JO - Przegl Lek VL - 53 IS - 4 N2 - In an attempt to test null hypothesis (Ho): that prenatal lead exposure does not increase the risk of prematurity and the delivery of SGA infants, a case-control study was performed in four hospitals of Southern Poland (Kraków, Rabka, Limanowa, Zakopane). Lead content was determined in maternal and cord blood as well as in head and pubic hair by the GF AAS (Perkin Elmer). A significant interregional variation of lead content in maternal blood was observed. Lead concentration in maternal and cord blood was significantly higher in the group of mothers of SGA newborns when compared to the controls. This was not the case with respect to the mothers of preterm infants. Also, the comparison of lead concentration in head and pubic hair revealed no statistically significant case-control differences. For a combined population of cases and controls, a significant gradient of lead concentration between maternal and cord blood was demonstrated. The correlation between lead content in different body compartments was observed. Conclusions. Different blood lead levels observed in mothers from four hospitals suggest different exposure. Higher lead concentration in maternal blood was associated with an increased risk of the delivery of SGA infant. SN - 0033-2240 UR - https://www.unboundmedicine.com/medline/citation/8711188/Prenatal_lead_exposure_and_the_pregnancy_outcome__A_case_control_study_in_southern_Poland_ L2 - http://www.diseaseinfosearch.org/result/5922 DB - PRIME DP - Unbound Medicine ER -