Tags

Type your tag names separated by a space and hit enter

The International Study of Asthma and Allergies in Childhood (ISAAC): objectives and methods; results from German ISAAC centres concerning traffic density and wheezing and allergic rhinitis.
Toxicol Lett. 1996 Aug; 86(2-3):99-103.TL

Abstract

The International Study of Asthma and Allergies in Childhood (ISAAC) was founded to maximize the value of epidemiological research into asthma and allergic disease by establishing a standardized methodology and facilitating international collaboration and comparison of data. The ISAAC design comprises three phases: Phase I uses validated core questionnaires designed to assess the prevalence and severity of asthma and allergic disease in defined populations; Phase II will investigate possible aetiological factors suggested by findings of Phase I and apply lung, blood and skin tests; Phase III will be a repetition of Phase I after 5 years to assess time trends in the prevalence and severity of wheezing, rhinitis and eczema in each ISAAC centre. In 1991 a survey on wheezing and allergic rhinitis in 2050 12-15 year old adolescents in Bochum showed a positive correlation between the prevalence of wheezing as well as allergic rhinitis and indicators of traffic density, controlling for putative confounders such as age, sex, passive smoking, active smoking, etc. In 1994-1995 an ISAAC Phase I survey conducted on adolescents in Münster, applying methodology similar to that in Bochum, found positive associations between surrogate measures of traffic density and 12 months prevalence of wheezing and lifetime prevalence of allergic rhinitis of a magnitude very close to that found in Bochum. The results from the two German cities provide support to the hypothesis that exposure to automobile emissions is related to wheezing and allergic rhinitis in children.

Authors+Show Affiliations

Keil U
Institut für Epidemiologie und Sozialmedizin, Universität Münster, Germany.
Weiland SK
No affiliation info available
Duhme H
No affiliation info available
Chambless L
No affiliation info available

MeSH

AdolescentAsthmaChildCross-Sectional StudiesData CollectionGermanyHumansInternational AgenciesOdds RatioPilot ProjectsPrevalenceRespiratory SoundsRhinitisVehicle Emissions

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8711784

Citation

Keil, U, et al. "The International Study of Asthma and Allergies in Childhood (ISAAC): Objectives and Methods; Results From German ISAAC Centres Concerning Traffic Density and Wheezing and Allergic Rhinitis." Toxicology Letters, vol. 86, no. 2-3, 1996, pp. 99-103.
Keil U, Weiland SK, Duhme H, et al. The International Study of Asthma and Allergies in Childhood (ISAAC): objectives and methods; results from German ISAAC centres concerning traffic density and wheezing and allergic rhinitis. Toxicol Lett. 1996;86(2-3):99-103.
Keil, U., Weiland, S. K., Duhme, H., & Chambless, L. (1996). The International Study of Asthma and Allergies in Childhood (ISAAC): objectives and methods; results from German ISAAC centres concerning traffic density and wheezing and allergic rhinitis. Toxicology Letters, 86(2-3), 99-103.
Keil U, et al. The International Study of Asthma and Allergies in Childhood (ISAAC): Objectives and Methods; Results From German ISAAC Centres Concerning Traffic Density and Wheezing and Allergic Rhinitis. Toxicol Lett. 1996;86(2-3):99-103. PubMed PMID: 8711784.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The International Study of Asthma and Allergies in Childhood (ISAAC): objectives and methods; results from German ISAAC centres concerning traffic density and wheezing and allergic rhinitis. AU - Keil,U, AU - Weiland,S K, AU - Duhme,H, AU - Chambless,L, PY - 1996/8/1/pubmed PY - 1996/8/1/medline PY - 1996/8/1/entrez SP - 99 EP - 103 JF - Toxicology letters JO - Toxicol Lett VL - 86 IS - 2-3 N2 - The International Study of Asthma and Allergies in Childhood (ISAAC) was founded to maximize the value of epidemiological research into asthma and allergic disease by establishing a standardized methodology and facilitating international collaboration and comparison of data. The ISAAC design comprises three phases: Phase I uses validated core questionnaires designed to assess the prevalence and severity of asthma and allergic disease in defined populations; Phase II will investigate possible aetiological factors suggested by findings of Phase I and apply lung, blood and skin tests; Phase III will be a repetition of Phase I after 5 years to assess time trends in the prevalence and severity of wheezing, rhinitis and eczema in each ISAAC centre. In 1991 a survey on wheezing and allergic rhinitis in 2050 12-15 year old adolescents in Bochum showed a positive correlation between the prevalence of wheezing as well as allergic rhinitis and indicators of traffic density, controlling for putative confounders such as age, sex, passive smoking, active smoking, etc. In 1994-1995 an ISAAC Phase I survey conducted on adolescents in Münster, applying methodology similar to that in Bochum, found positive associations between surrogate measures of traffic density and 12 months prevalence of wheezing and lifetime prevalence of allergic rhinitis of a magnitude very close to that found in Bochum. The results from the two German cities provide support to the hypothesis that exposure to automobile emissions is related to wheezing and allergic rhinitis in children. SN - 0378-4274 UR - https://www.unboundmedicine.com/medline/citation/8711784/The_International_Study_of_Asthma_and_Allergies_in_Childhood__ISAAC_:_objectives_and_methods DB - PRIME DP - Unbound Medicine ER -