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Treatment of secondary lymphedema of the upper limb with CYCLO 3 FORT.
Lymphology. 1996 Mar; 29(1):29-35.L

Abstract

Fifty seven patients with secondary lymphedema of the upper limb after previous treatment for breast cancer were treated for 3 months with an extract of Ruscus + Hesperidin Methyl Chalcone (CYCLO 3 FORT) or placebo according to a double-blind protocol in the context of a controlled clinical trial. All patients also underwent manual lymphatic drainage twice a week for at least one month. With CYCLO 3 FORT, the reduction in volume of arm edema, the main assessment criteria, was 12.9% after 3 months of treatment as compared with a placebo (p=0.009). Decreased edema tended to be more marked in the forearm compared with the upper arm where excess fat deposition seemed to dominate over excess fluid accumulation. CYCLO 3 FORT was well tolerated with minimal adverse reaction.

Authors+Show Affiliations

Unité de Lymphologie, Hôpital Cognacq-Jay, Paris, France.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

8721977

Citation

Cluzan, R V., et al. "Treatment of Secondary Lymphedema of the Upper Limb With CYCLO 3 FORT." Lymphology, vol. 29, no. 1, 1996, pp. 29-35.
Cluzan RV, Alliot F, Ghabboun S, et al. Treatment of secondary lymphedema of the upper limb with CYCLO 3 FORT. Lymphology. 1996;29(1):29-35.
Cluzan, R. V., Alliot, F., Ghabboun, S., & Pascot, M. (1996). Treatment of secondary lymphedema of the upper limb with CYCLO 3 FORT. Lymphology, 29(1), 29-35.
Cluzan RV, et al. Treatment of Secondary Lymphedema of the Upper Limb With CYCLO 3 FORT. Lymphology. 1996;29(1):29-35. PubMed PMID: 8721977.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Treatment of secondary lymphedema of the upper limb with CYCLO 3 FORT. AU - Cluzan,R V, AU - Alliot,F, AU - Ghabboun,S, AU - Pascot,M, PY - 1996/3/1/pubmed PY - 1996/3/1/medline PY - 1996/3/1/entrez SP - 29 EP - 35 JF - Lymphology JO - Lymphology VL - 29 IS - 1 N2 - Fifty seven patients with secondary lymphedema of the upper limb after previous treatment for breast cancer were treated for 3 months with an extract of Ruscus + Hesperidin Methyl Chalcone (CYCLO 3 FORT) or placebo according to a double-blind protocol in the context of a controlled clinical trial. All patients also underwent manual lymphatic drainage twice a week for at least one month. With CYCLO 3 FORT, the reduction in volume of arm edema, the main assessment criteria, was 12.9% after 3 months of treatment as compared with a placebo (p=0.009). Decreased edema tended to be more marked in the forearm compared with the upper arm where excess fat deposition seemed to dominate over excess fluid accumulation. CYCLO 3 FORT was well tolerated with minimal adverse reaction. SN - 0024-7766 UR - https://www.unboundmedicine.com/medline/citation/8721977/Treatment_of_secondary_lymphedema_of_the_upper_limb_with_CYCLO_3_FORT_ L2 - http://www.diseaseinfosearch.org/result/4355 DB - PRIME DP - Unbound Medicine ER -