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[Variations in the molecular forms of LH and FSH during the normal ovarian cycle].
Ginecol Obstet Mex. 1996 Mar; 64:140-5.GO

Abstract

FSH and LH concentrations during the menstrual cycle are well known, showing characteristically a midcycle surge in LH as well as in less degree in FSH. At the present there is an increasing interest in studying variations of the moleculoar forms of both gonadotropins. We have studied the chromatographic profile of FSH and LH in sera obtained from women regularly ovulating and in patients with anovulatory cycles by the use of gel column chromatography. It was observed the predominance of LH 32-34 kDa at midcycle and the heterogeneous FSH profile during the ovarian cycle. In sera from anovulatory patients the chromatographic profile was even more irregular for both LH and FSH. It is concluded that LH 32-34 kDa may be the more biological isoform in turn related with the process of ovulation.

Authors+Show Affiliations

Unidad de Investigación Médica en Enfermedades Endócrinas, Hospital de Especialidades, México.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

spa

PubMed ID

8729192

Citation

Hernandez-Valencia, M, et al. "[Variations in the Molecular Forms of LH and FSH During the Normal Ovarian Cycle]." Ginecologia Y Obstetricia De Mexico, vol. 64, 1996, pp. 140-5.
Hernandez-Valencia M, Mason M, Eugenia Fonseca M, et al. [Variations in the molecular forms of LH and FSH during the normal ovarian cycle]. Ginecol Obstet Mex. 1996;64:140-5.
Hernandez-Valencia, M., Mason, M., Eugenia Fonseca, M., & Zarate, A. (1996). [Variations in the molecular forms of LH and FSH during the normal ovarian cycle]. Ginecologia Y Obstetricia De Mexico, 64, 140-5.
Hernandez-Valencia M, et al. [Variations in the Molecular Forms of LH and FSH During the Normal Ovarian Cycle]. Ginecol Obstet Mex. 1996;64:140-5. PubMed PMID: 8729192.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Variations in the molecular forms of LH and FSH during the normal ovarian cycle]. AU - Hernandez-Valencia,M, AU - Mason,M, AU - Eugenia Fonseca,M, AU - Zarate,A, PY - 1996/3/1/pubmed PY - 1996/3/1/medline PY - 1996/3/1/entrez SP - 140 EP - 5 JF - Ginecologia y obstetricia de Mexico JO - Ginecol Obstet Mex VL - 64 N2 - FSH and LH concentrations during the menstrual cycle are well known, showing characteristically a midcycle surge in LH as well as in less degree in FSH. At the present there is an increasing interest in studying variations of the moleculoar forms of both gonadotropins. We have studied the chromatographic profile of FSH and LH in sera obtained from women regularly ovulating and in patients with anovulatory cycles by the use of gel column chromatography. It was observed the predominance of LH 32-34 kDa at midcycle and the heterogeneous FSH profile during the ovarian cycle. In sera from anovulatory patients the chromatographic profile was even more irregular for both LH and FSH. It is concluded that LH 32-34 kDa may be the more biological isoform in turn related with the process of ovulation. SN - 0300-9041 UR - https://www.unboundmedicine.com/medline/citation/8729192/[Variations_in_the_molecular_forms_of_LH_and_FSH_during_the_normal_ovarian_cycle]_ DB - PRIME DP - Unbound Medicine ER -