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Feeding of premature infant formula after hospital discharge of infants weighing less than 1800 grams at birth.
J Perinatol. 1996 Mar-Apr; 16(2 Pt 1):111-6.JP

Abstract

A randomized, double-blind study was conducted to determine whether continued feeding of premature infant formula after hospital discharge improve biochemical measures of bone mineral or protein status and anthropometrics during the first 8 and 12 weeks, respectively, after initial hospital discharge. Forty-three subjects were randomized to receive either a 20 kcal/ounce standard cow's milk-based formula with iron or a 20 kcal/ounce premature infant formula with iron for 8 weeks after hospital discharge. Sixteen exclusively breast-fed infants (mother's own milk) who received a multivitamin supplement with iron were compared with infants in both formula groups. There were no differences among the three groups in gender, birth weight, gestational age, or weight and age at the time of study entry. Alkaline phosphatase values were lower in infants receiving premature infant formula than in those receiving standard formula 8 weeks after discharge. Phosphorus values were lower and alkaline phosphatase values higher in the human milk-fed group than in both formula groups 8 weeks after discharge despite supplementation with calcium, phosphorus, and vitamin D before and during the study. At 8 weeks after discharge, human milk-fed infants also had lower transferrin levels than infants fed formulas. Infants in both formula groups grew similarly in weight, whereas the infants fed human milk weighed less throughout the study. The group fed premature infant formula had greater mean length and head circumference than the standard formula or human milk-fed groups. These data indicate that premature infants weighing < 1800 gm at birth may benefit from the continuation of premature infant formula during the first 8 weeks after initial hospital discharge.

Authors+Show Affiliations

Children's Mercy Hospital, University of Missouri Kansas City, USA.No affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

8732558

Citation

Wheeler, R E., and R T. Hall. "Feeding of Premature Infant Formula After Hospital Discharge of Infants Weighing Less Than 1800 Grams at Birth." Journal of Perinatology : Official Journal of the California Perinatal Association, vol. 16, no. 2 Pt 1, 1996, pp. 111-6.
Wheeler RE, Hall RT. Feeding of premature infant formula after hospital discharge of infants weighing less than 1800 grams at birth. J Perinatol. 1996;16(2 Pt 1):111-6.
Wheeler, R. E., & Hall, R. T. (1996). Feeding of premature infant formula after hospital discharge of infants weighing less than 1800 grams at birth. Journal of Perinatology : Official Journal of the California Perinatal Association, 16(2 Pt 1), 111-6.
Wheeler RE, Hall RT. Feeding of Premature Infant Formula After Hospital Discharge of Infants Weighing Less Than 1800 Grams at Birth. J Perinatol. 1996;16(2 Pt 1):111-6. PubMed PMID: 8732558.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Feeding of premature infant formula after hospital discharge of infants weighing less than 1800 grams at birth. AU - Wheeler,R E, AU - Hall,R T, PY - 1996/3/1/pubmed PY - 1996/3/1/medline PY - 1996/3/1/entrez SP - 111 EP - 6 JF - Journal of perinatology : official journal of the California Perinatal Association JO - J Perinatol VL - 16 IS - 2 Pt 1 N2 - A randomized, double-blind study was conducted to determine whether continued feeding of premature infant formula after hospital discharge improve biochemical measures of bone mineral or protein status and anthropometrics during the first 8 and 12 weeks, respectively, after initial hospital discharge. Forty-three subjects were randomized to receive either a 20 kcal/ounce standard cow's milk-based formula with iron or a 20 kcal/ounce premature infant formula with iron for 8 weeks after hospital discharge. Sixteen exclusively breast-fed infants (mother's own milk) who received a multivitamin supplement with iron were compared with infants in both formula groups. There were no differences among the three groups in gender, birth weight, gestational age, or weight and age at the time of study entry. Alkaline phosphatase values were lower in infants receiving premature infant formula than in those receiving standard formula 8 weeks after discharge. Phosphorus values were lower and alkaline phosphatase values higher in the human milk-fed group than in both formula groups 8 weeks after discharge despite supplementation with calcium, phosphorus, and vitamin D before and during the study. At 8 weeks after discharge, human milk-fed infants also had lower transferrin levels than infants fed formulas. Infants in both formula groups grew similarly in weight, whereas the infants fed human milk weighed less throughout the study. The group fed premature infant formula had greater mean length and head circumference than the standard formula or human milk-fed groups. These data indicate that premature infants weighing < 1800 gm at birth may benefit from the continuation of premature infant formula during the first 8 weeks after initial hospital discharge. SN - 0743-8346 UR - https://www.unboundmedicine.com/medline/citation/8732558/Feeding_of_premature_infant_formula_after_hospital_discharge_of_infants_weighing_less_than_1800_grams_at_birth_ L2 - https://medlineplus.gov/prematurebabies.html DB - PRIME DP - Unbound Medicine ER -