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Clinical presentation and treatment of migraine.
Clin Ther 1996 Mar-Apr; 18(2):229-45; discussion 228CT

Abstract

The pathogenesis of migraine is not completely understood but may involve vasodilation of cerebral blood vessels and/or the release of vasoactive neuropeptides (ie, norepinephrine) from the perivascular axons in the dura mater after activation of the trigeminovascular system. Many environmental factors and physiologic influences may provoke a migraine or increase its severity. The typical migraine headache without aura is unilateral, pulsating, of moderate-to-severe intensity, and aggravated by physical activity. Migraine prevention is best achieved by avoidance of known migraine triggers or enhancers and by reducing the amount of lifestyle stressors. Pharmacotherapeutic options in the treatment of migraine are discussed herein.

Authors+Show Affiliations

College of Pharmacy, Washington State University, Pullman, USA.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

8733984

Citation

Skaer, T L.. "Clinical Presentation and Treatment of Migraine." Clinical Therapeutics, vol. 18, no. 2, 1996, pp. 229-45; discussion 228.
Skaer TL. Clinical presentation and treatment of migraine. Clin Ther. 1996;18(2):229-45; discussion 228.
Skaer, T. L. (1996). Clinical presentation and treatment of migraine. Clinical Therapeutics, 18(2), pp. 229-45; discussion 228.
Skaer TL. Clinical Presentation and Treatment of Migraine. Clin Ther. 1996;18(2):229-45; discussion 228. PubMed PMID: 8733984.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical presentation and treatment of migraine. A1 - Skaer,T L, PY - 1996/3/1/pubmed PY - 1996/3/1/medline PY - 1996/3/1/entrez SP - 229-45; discussion 228 JF - Clinical therapeutics JO - Clin Ther VL - 18 IS - 2 N2 - The pathogenesis of migraine is not completely understood but may involve vasodilation of cerebral blood vessels and/or the release of vasoactive neuropeptides (ie, norepinephrine) from the perivascular axons in the dura mater after activation of the trigeminovascular system. Many environmental factors and physiologic influences may provoke a migraine or increase its severity. The typical migraine headache without aura is unilateral, pulsating, of moderate-to-severe intensity, and aggravated by physical activity. Migraine prevention is best achieved by avoidance of known migraine triggers or enhancers and by reducing the amount of lifestyle stressors. Pharmacotherapeutic options in the treatment of migraine are discussed herein. SN - 0149-2918 UR - https://www.unboundmedicine.com/medline/citation/8733984/Clinical_presentation_and_treatment_of_migraine_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0149-2918(96)80004-X DB - PRIME DP - Unbound Medicine ER -