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Gastro-oesophageal reflux before and after vertical banded gastroplasty in the treatment of obesity.

Abstract

OBJECTIVE

To study the long term effect of vertical banded gastroplasty on lower oesophageal sphincter pressure.

DESIGN

Prospective study.

SETTING

University hospital, Sweden.

SUBJECTS

21 morbidly obese patients (mean body mass index 42.5).

INTERVENTIONS

Vertical banded gastroplasty, together with measurements of endoscopic grade, oesophageal manometry, and 24 hour pH before, and a mean of 38 months after, operation.

MAIN OUTCOME MEASURES

Weight, grade of oesophagitis according to the Savary-Miller classification, number of episodes of reflux, percentage of time that the pH was < 4, and lower oesophageal sphincter pressure.

RESULTS

Before operation 5/14 patients (36%) had evidence of oesophagitis, and 12/21 (57%) had evidence of reflux disease. Two patients had abnormally low lower oesophageal sphincter pressure (< 10 mm Hg). A mean (SEM) of 32 months after operation (range 6-49) the mean body mass index was 32.7 (1.2), and after a mean of 38 months paired data showed that there had been no significant changes in manometric (n = 11) or 24 hour pH (n = 10) measurements, or in endoscopic grading (n = 7).

CONCLUSION

Vertical banded gastroplasty used in the treatment of morbid obesity does not affect the antireflux function of the lower oesophageal sphincter.

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Authors+Show Affiliations

,

Department of Surgery, Karolinska Institute at Danderyd Hospital, Stockholm, Sweden.

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Source

MeSH

Esophagitis, Peptic
Esophagogastric Junction
Female
Follow-Up Studies
Gastroesophageal Reflux
Gastroplasty
Humans
Hydrogen-Ion Concentration
Male
Manometry
Middle Aged
Obesity, Morbid
Pressure
Prospective Studies
Time Factors

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8739417

Citation

Näslund, E, et al. "Gastro-oesophageal Reflux Before and After Vertical Banded Gastroplasty in the Treatment of Obesity." The European Journal of Surgery = Acta Chirurgica, vol. 162, no. 4, 1996, pp. 303-6.
Näslund E, Granström L, Melcher A, et al. Gastro-oesophageal reflux before and after vertical banded gastroplasty in the treatment of obesity. Eur J Surg. 1996;162(4):303-6.
Näslund, E., Granström, L., Melcher, A., Stockeld, D., & Backman, L. (1996). Gastro-oesophageal reflux before and after vertical banded gastroplasty in the treatment of obesity. The European Journal of Surgery = Acta Chirurgica, 162(4), pp. 303-6.
Näslund E, et al. Gastro-oesophageal Reflux Before and After Vertical Banded Gastroplasty in the Treatment of Obesity. Eur J Surg. 1996;162(4):303-6. PubMed PMID: 8739417.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Gastro-oesophageal reflux before and after vertical banded gastroplasty in the treatment of obesity. AU - Näslund,E, AU - Granström,L, AU - Melcher,A, AU - Stockeld,D, AU - Backman,L, PY - 1996/4/1/pubmed PY - 1996/4/1/medline PY - 1996/4/1/entrez SP - 303 EP - 6 JF - The European journal of surgery = Acta chirurgica JO - Eur J Surg VL - 162 IS - 4 N2 - OBJECTIVE: To study the long term effect of vertical banded gastroplasty on lower oesophageal sphincter pressure. DESIGN: Prospective study. SETTING: University hospital, Sweden. SUBJECTS: 21 morbidly obese patients (mean body mass index 42.5). INTERVENTIONS: Vertical banded gastroplasty, together with measurements of endoscopic grade, oesophageal manometry, and 24 hour pH before, and a mean of 38 months after, operation. MAIN OUTCOME MEASURES: Weight, grade of oesophagitis according to the Savary-Miller classification, number of episodes of reflux, percentage of time that the pH was < 4, and lower oesophageal sphincter pressure. RESULTS: Before operation 5/14 patients (36%) had evidence of oesophagitis, and 12/21 (57%) had evidence of reflux disease. Two patients had abnormally low lower oesophageal sphincter pressure (< 10 mm Hg). A mean (SEM) of 32 months after operation (range 6-49) the mean body mass index was 32.7 (1.2), and after a mean of 38 months paired data showed that there had been no significant changes in manometric (n = 11) or 24 hour pH (n = 10) measurements, or in endoscopic grading (n = 7). CONCLUSION: Vertical banded gastroplasty used in the treatment of morbid obesity does not affect the antireflux function of the lower oesophageal sphincter. SN - 1102-4151 UR - https://www.unboundmedicine.com/medline/citation/8739417/Gastro_oesophageal_reflux_before_and_after_vertical_banded_gastroplasty_in_the_treatment_of_obesity_ L2 - http://www.diseaseinfosearch.org/result/9028 DB - PRIME DP - Unbound Medicine ER -