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Characterization of cellular components in the peritoneal fluid and in the endometrial tissue of women with endometriosis.
Arch Immunol Ther Exp (Warsz). 1995; 43(5-6):247-52.AI

Abstract

The presence of leukocyte subpopulations was demonstrated in peritoneal fluid and in endometrial tissue of women with (n = 16) and without (n = 20) endometriosis. Peritoneal fluid samples were also assayed for effects on lymphocyte proliferation in vitro. Peritoneal fluid leukocyte profiles were observed to be different between these groups. The most significant elevations in total number of leukocytes, macrophages and lymphocytes and natural killer (NK) cells were observed in women with endometriosis. In normal eutopic endometrium T lymphocytes (CD3+), macrophages (Ki-M1+) and NK cells (CD16- CD5+) were present. In contrast aggregates of NK cells (CD16+ CD56-) were only identified in ectopic endometrial tissue. Mitogen-induced lymphocyte proliferation was significantly higher in the presence of peritoneal fluid from patients with severe stage of endometriosis as compared with other samples. Our data indicate that disturbances of the cellular immune system may lead to progression of endometriosis in female peritoneal cavity.

Authors+Show Affiliations

Department of Obstetrics and Gynecology, Medical Academy, Lublin, Poland.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8744643

Citation

Kamiński, K, et al. "Characterization of Cellular Components in the Peritoneal Fluid and in the Endometrial Tissue of Women With Endometriosis." Archivum Immunologiae Et Therapiae Experimentalis, vol. 43, no. 5-6, 1995, pp. 247-52.
Kamiński K, Kotarski J, Gogacz M. Characterization of cellular components in the peritoneal fluid and in the endometrial tissue of women with endometriosis. Arch Immunol Ther Exp (Warsz). 1995;43(5-6):247-52.
Kamiński, K., Kotarski, J., & Gogacz, M. (1995). Characterization of cellular components in the peritoneal fluid and in the endometrial tissue of women with endometriosis. Archivum Immunologiae Et Therapiae Experimentalis, 43(5-6), 247-52.
Kamiński K, Kotarski J, Gogacz M. Characterization of Cellular Components in the Peritoneal Fluid and in the Endometrial Tissue of Women With Endometriosis. Arch Immunol Ther Exp (Warsz). 1995;43(5-6):247-52. PubMed PMID: 8744643.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Characterization of cellular components in the peritoneal fluid and in the endometrial tissue of women with endometriosis. AU - Kamiński,K, AU - Kotarski,J, AU - Gogacz,M, PY - 1995/1/1/pubmed PY - 1995/1/1/medline PY - 1995/1/1/entrez SP - 247 EP - 52 JF - Archivum immunologiae et therapiae experimentalis JO - Arch. Immunol. Ther. Exp. (Warsz.) VL - 43 IS - 5-6 N2 - The presence of leukocyte subpopulations was demonstrated in peritoneal fluid and in endometrial tissue of women with (n = 16) and without (n = 20) endometriosis. Peritoneal fluid samples were also assayed for effects on lymphocyte proliferation in vitro. Peritoneal fluid leukocyte profiles were observed to be different between these groups. The most significant elevations in total number of leukocytes, macrophages and lymphocytes and natural killer (NK) cells were observed in women with endometriosis. In normal eutopic endometrium T lymphocytes (CD3+), macrophages (Ki-M1+) and NK cells (CD16- CD5+) were present. In contrast aggregates of NK cells (CD16+ CD56-) were only identified in ectopic endometrial tissue. Mitogen-induced lymphocyte proliferation was significantly higher in the presence of peritoneal fluid from patients with severe stage of endometriosis as compared with other samples. Our data indicate that disturbances of the cellular immune system may lead to progression of endometriosis in female peritoneal cavity. SN - 0004-069X UR - https://www.unboundmedicine.com/medline/citation/8744643/Characterization_of_cellular_components_in_the_peritoneal_fluid_and_in_the_endometrial_tissue_of_women_with_endometriosis_ L2 - http://www.diseaseinfosearch.org/result/2537 DB - PRIME DP - Unbound Medicine ER -