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[Endoscopic ligation of esophageal varices: prevention of hemorrhagic recurrences caused by rupture of esophageal varices. Results in 45 patients].
Gastroenterol Clin Biol. 1995 Nov; 19(11):909-13.GC

Abstract

OBJECTIVES

The aim of this study was to assess the morbidity and efficacy of endoscopic variceal ligation for the prophylaxis of rebleeding from oesophageal varices.

METHODS

Forty-five patients with cirrhosis (Child's class: A: 18, B: 16, C: 11) and recent (< 48 h) variceal bleeding were included. Eleven of the patients were included after failure of sclerotherapy. All patients were treated by endoscopic ligation until the complete eradication of oesophageal varices. The mean follow-up was 8.7 +/- 6.8 months.

RESULTS

Oesophageal varices were eradicated in 40 patients (89%) after an average of 2 sessions (range: 1-5). In a subset of 11 patients treated after failure of sclerotherapy, 8 (73%) had complete eradication of oesophageal varices. Six of the 45 patients (13%) had recurrence of haemorrhage, due to post-ligation ulcerations in 5 cases and to rupture of oesophageal varices in one case. The rate of complications was 7%. Of the 40 patients whose oesophageal varices were eradicated, 7 (17%) were lost for follow up, and another treatment was performed in 4 (10%): liver transplantation in 2, and transjugular intrahepatic portosystemic shunt in 2. Recurrence of oesophageal varices after eradication was observed in 3 (10%) of the remaining 29 patients after a follow-up of 8.9 +/- 12.9 months. Of these 3 patients, only one (3%) presented with recurrence of haemorrhage due to ruptured oesophageal varices. Three patients (7%) died before eradication of oesophageal varices from causes unrelated to the technique.

CONCLUSION

This study confirms that endoscopic ligation is effective for eradication of oesophageal varices, with a low morbidity. This technique appears to be a method of choice in the prophylaxis of rebleeding from oesophageal varices, especially when sclerotherapy is ineffective.

Authors+Show Affiliations

Service d'Hépato-Gastroentérologie, Hôtel-Dieu, Lyon.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

fre

PubMed ID

8746050

Citation

Bizollon, T, et al. "[Endoscopic Ligation of Esophageal Varices: Prevention of Hemorrhagic Recurrences Caused By Rupture of Esophageal Varices. Results in 45 Patients]." Gastroenterologie Clinique Et Biologique, vol. 19, no. 11, 1995, pp. 909-13.
Bizollon T, Gaudin JL, Jacob P, et al. [Endoscopic ligation of esophageal varices: prevention of hemorrhagic recurrences caused by rupture of esophageal varices. Results in 45 patients]. Gastroenterol Clin Biol. 1995;19(11):909-13.
Bizollon, T., Gaudin, J. L., Jacob, P., Bouvet, B., Evreux, M., Souquet, J. C., & Trépo, C. (1995). [Endoscopic ligation of esophageal varices: prevention of hemorrhagic recurrences caused by rupture of esophageal varices. Results in 45 patients]. Gastroenterologie Clinique Et Biologique, 19(11), 909-13.
Bizollon T, et al. [Endoscopic Ligation of Esophageal Varices: Prevention of Hemorrhagic Recurrences Caused By Rupture of Esophageal Varices. Results in 45 Patients]. Gastroenterol Clin Biol. 1995;19(11):909-13. PubMed PMID: 8746050.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Endoscopic ligation of esophageal varices: prevention of hemorrhagic recurrences caused by rupture of esophageal varices. Results in 45 patients]. AU - Bizollon,T, AU - Gaudin,J L, AU - Jacob,P, AU - Bouvet,B, AU - Evreux,M, AU - Souquet,J C, AU - Trépo,C, PY - 1995/11/1/pubmed PY - 1995/11/1/medline PY - 1995/11/1/entrez SP - 909 EP - 13 JF - Gastroenterologie clinique et biologique JO - Gastroenterol Clin Biol VL - 19 IS - 11 N2 - OBJECTIVES: The aim of this study was to assess the morbidity and efficacy of endoscopic variceal ligation for the prophylaxis of rebleeding from oesophageal varices. METHODS: Forty-five patients with cirrhosis (Child's class: A: 18, B: 16, C: 11) and recent (< 48 h) variceal bleeding were included. Eleven of the patients were included after failure of sclerotherapy. All patients were treated by endoscopic ligation until the complete eradication of oesophageal varices. The mean follow-up was 8.7 +/- 6.8 months. RESULTS: Oesophageal varices were eradicated in 40 patients (89%) after an average of 2 sessions (range: 1-5). In a subset of 11 patients treated after failure of sclerotherapy, 8 (73%) had complete eradication of oesophageal varices. Six of the 45 patients (13%) had recurrence of haemorrhage, due to post-ligation ulcerations in 5 cases and to rupture of oesophageal varices in one case. The rate of complications was 7%. Of the 40 patients whose oesophageal varices were eradicated, 7 (17%) were lost for follow up, and another treatment was performed in 4 (10%): liver transplantation in 2, and transjugular intrahepatic portosystemic shunt in 2. Recurrence of oesophageal varices after eradication was observed in 3 (10%) of the remaining 29 patients after a follow-up of 8.9 +/- 12.9 months. Of these 3 patients, only one (3%) presented with recurrence of haemorrhage due to ruptured oesophageal varices. Three patients (7%) died before eradication of oesophageal varices from causes unrelated to the technique. CONCLUSION: This study confirms that endoscopic ligation is effective for eradication of oesophageal varices, with a low morbidity. This technique appears to be a method of choice in the prophylaxis of rebleeding from oesophageal varices, especially when sclerotherapy is ineffective. SN - 0399-8320 UR - https://www.unboundmedicine.com/medline/citation/8746050/[Endoscopic_ligation_of_esophageal_varices:_prevention_of_hemorrhagic_recurrences_caused_by_rupture_of_esophageal_varices__Results_in_45_patients]_ L2 - http://www.diseaseinfosearch.org/result/2658 DB - PRIME DP - Unbound Medicine ER -