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Outbreak of TEM-24-producing Enterobacter aerogenes in an intensive care unit and dissemination of the extended-spectrum beta-lactamase to other members of the family enterobacteriaceae.
J Clin Microbiol. 1996 Jan; 34(1):76-9.JC

Abstract

We report an outbreak of Enterobacter aerogenes in an intensive care unit (ICU) and two medicine departments that produced the extended-spectrum beta-lactamase TEM-24, which was difficult to detect by disk agar diffusion. The strains were compared by DNA restriction fragment length polymorphism after pulsed-field gel electrophoresis following cleavage with XbaI. This typing method indicated that a single strain, first isolated in the ICU, spread throughout the other medical departments as a result of patient transfer. We also observed the transfer in vivo of the plasmid encoding TEM-24 from the strain of Enterobacter aerogenes to different strains of Escherichia coli and Citrobacter freundii in the ICU. It therefore appears that the epidemic involved results from two events: dissemination of one strain of Enterobacter aerogenes and dissemination of the plasmid encoding TEM-24 among various members of the family Enterobacteriaceae.

Authors+Show Affiliations

Laboratoire de Bactériologie, Hôpital Universitaire du Bocage, Dijon, France.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8748277

Citation

Neuwirth, C, et al. "Outbreak of TEM-24-producing Enterobacter Aerogenes in an Intensive Care Unit and Dissemination of the Extended-spectrum Beta-lactamase to Other Members of the Family Enterobacteriaceae." Journal of Clinical Microbiology, vol. 34, no. 1, 1996, pp. 76-9.
Neuwirth C, Siebor E, Lopez J, et al. Outbreak of TEM-24-producing Enterobacter aerogenes in an intensive care unit and dissemination of the extended-spectrum beta-lactamase to other members of the family enterobacteriaceae. J Clin Microbiol. 1996;34(1):76-9.
Neuwirth, C., Siebor, E., Lopez, J., Pechinot, A., & Kazmierczak, A. (1996). Outbreak of TEM-24-producing Enterobacter aerogenes in an intensive care unit and dissemination of the extended-spectrum beta-lactamase to other members of the family enterobacteriaceae. Journal of Clinical Microbiology, 34(1), 76-9.
Neuwirth C, et al. Outbreak of TEM-24-producing Enterobacter Aerogenes in an Intensive Care Unit and Dissemination of the Extended-spectrum Beta-lactamase to Other Members of the Family Enterobacteriaceae. J Clin Microbiol. 1996;34(1):76-9. PubMed PMID: 8748277.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Outbreak of TEM-24-producing Enterobacter aerogenes in an intensive care unit and dissemination of the extended-spectrum beta-lactamase to other members of the family enterobacteriaceae. AU - Neuwirth,C, AU - Siebor,E, AU - Lopez,J, AU - Pechinot,A, AU - Kazmierczak,A, PY - 1996/1/1/pubmed PY - 1996/1/1/medline PY - 1996/1/1/entrez SP - 76 EP - 9 JF - Journal of clinical microbiology JO - J. Clin. Microbiol. VL - 34 IS - 1 N2 - We report an outbreak of Enterobacter aerogenes in an intensive care unit (ICU) and two medicine departments that produced the extended-spectrum beta-lactamase TEM-24, which was difficult to detect by disk agar diffusion. The strains were compared by DNA restriction fragment length polymorphism after pulsed-field gel electrophoresis following cleavage with XbaI. This typing method indicated that a single strain, first isolated in the ICU, spread throughout the other medical departments as a result of patient transfer. We also observed the transfer in vivo of the plasmid encoding TEM-24 from the strain of Enterobacter aerogenes to different strains of Escherichia coli and Citrobacter freundii in the ICU. It therefore appears that the epidemic involved results from two events: dissemination of one strain of Enterobacter aerogenes and dissemination of the plasmid encoding TEM-24 among various members of the family Enterobacteriaceae. SN - 0095-1137 UR - https://www.unboundmedicine.com/medline/citation/8748277/Outbreak_of_TEM_24_producing_Enterobacter_aerogenes_in_an_intensive_care_unit_and_dissemination_of_the_extended_spectrum_beta_lactamase_to_other_members_of_the_family_enterobacteriaceae_ L2 - http://jcm.asm.org/cgi/pmidlookup?view=long&pmid=8748277 DB - PRIME DP - Unbound Medicine ER -