Tags

Type your tag names separated by a space and hit enter

[Polycystic ovary syndrome: a disorder of insulin action and an increased risk for onset of non-insulin-dependent diabetes].
Lijec Vjesn 1996; 118 Suppl 1:28-32LV

Abstract

Hyperandrogenemia may be the most common endocrinopathy in women, affecting up to 10% of all women and as many as 30% of certain subgroups. Women with polycystic ovary syndrome have a unique disorder of insulin action and are at increased risk to develop NIDDM. NIDDM in women with PCOS has earlier age of onset than it does in the general population. Insulin-induced receptor autophosphorylation is diminished in 50% of PCOS women. PCOS may be a disease of abnormal protein tyrosine kinase receptor signaling. IGF-I and IGF-II play an important role in regulating ovarian androgen production via receptors.

Authors+Show Affiliations

Aganović I
Zavod za endokrinologiju, dijabetes i bolesti metabolizma Klinike za unutarnje bolesti, KBC Rebro, Zagreb.
Jelcić J
No affiliation info available
Kozić-Rukavina B
No affiliation info available

MeSH

Diabetes Mellitus, Type 2FemaleHumansInsulin ResistancePolycystic Ovary SyndromeRisk Factors

Pub Type(s)

English Abstract
Journal Article

Language

hrv

PubMed ID

8759405

Citation

Aganović, I, et al. "[Polycystic Ovary Syndrome: a Disorder of Insulin Action and an Increased Risk for Onset of Non-insulin-dependent Diabetes]." Lijecnicki Vjesnik, vol. 118 Suppl 1, 1996, pp. 28-32.
Aganović I, Jelcić J, Kozić-Rukavina B. [Polycystic ovary syndrome: a disorder of insulin action and an increased risk for onset of non-insulin-dependent diabetes]. Lijec Vjesn. 1996;118 Suppl 1:28-32.
Aganović, I., Jelcić, J., & Kozić-Rukavina, B. (1996). [Polycystic ovary syndrome: a disorder of insulin action and an increased risk for onset of non-insulin-dependent diabetes]. Lijecnicki Vjesnik, 118 Suppl 1, pp. 28-32.
Aganović I, Jelcić J, Kozić-Rukavina B. [Polycystic Ovary Syndrome: a Disorder of Insulin Action and an Increased Risk for Onset of Non-insulin-dependent Diabetes]. Lijec Vjesn. 1996;118 Suppl 1:28-32. PubMed PMID: 8759405.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Polycystic ovary syndrome: a disorder of insulin action and an increased risk for onset of non-insulin-dependent diabetes]. AU - Aganović,I, AU - Jelcić,J, AU - Kozić-Rukavina,B, PY - 1996/3/1/pubmed PY - 1996/3/1/medline PY - 1996/3/1/entrez SP - 28 EP - 32 JF - Lijecnicki vjesnik JO - Lijec Vjesn VL - 118 Suppl 1 N2 - Hyperandrogenemia may be the most common endocrinopathy in women, affecting up to 10% of all women and as many as 30% of certain subgroups. Women with polycystic ovary syndrome have a unique disorder of insulin action and are at increased risk to develop NIDDM. NIDDM in women with PCOS has earlier age of onset than it does in the general population. Insulin-induced receptor autophosphorylation is diminished in 50% of PCOS women. PCOS may be a disease of abnormal protein tyrosine kinase receptor signaling. IGF-I and IGF-II play an important role in regulating ovarian androgen production via receptors. SN - 0024-3477 UR - https://www.unboundmedicine.com/medline/citation/8759405/[Polycystic_ovary_syndrome:_a_disorder_of_insulin_action_and_an_increased_risk_for_onset_of_non_insulin_dependent_diabetes]_ L2 - http://www.diseaseinfosearch.org/result/2236 DB - PRIME DP - Unbound Medicine ER -