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HLA and bird breeder's hypersensitivity pneumonitis.
Monogr Allergy. 1977; 11:45-54.MA

Abstract

HLA antigen status was assessed in non-related individuals and related family members with bird breeder's hypersensitivity pneumonitis (HP). 35% of 20 non-related patients carried HLABW40 compared to 10% of 861 normal controls (p less than 0.001, Pc less than 0.05, respectively). A consistent association of an HLA haplotype with disease was demonstrated in three of four families. Selected HLA antisera contained antibodies which blocked the blastogenic response to bird antigen. This study suggests the existence of an HLA associated Ir gene in bird breeder's HP.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

876124

Citation

Allen, D H., et al. "HLA and Bird Breeder's Hypersensitivity Pneumonitis." Monographs in Allergy, vol. 11, 1977, pp. 45-54.
Allen DH, Basten A, Woolcock AJ, et al. HLA and bird breeder's hypersensitivity pneumonitis. Monogr Allergy. 1977;11:45-54.
Allen, D. H., Basten, A., Woolcock, A. J., & Guinan, J. (1977). HLA and bird breeder's hypersensitivity pneumonitis. Monographs in Allergy, 11, 45-54.
Allen DH, et al. HLA and Bird Breeder's Hypersensitivity Pneumonitis. Monogr Allergy. 1977;11:45-54. PubMed PMID: 876124.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - HLA and bird breeder's hypersensitivity pneumonitis. AU - Allen,D H, AU - Basten,A, AU - Woolcock,A J, AU - Guinan,J, PY - 1977/1/1/pubmed PY - 1977/1/1/medline PY - 1977/1/1/entrez SP - 45 EP - 54 JF - Monographs in allergy JO - Monogr Allergy VL - 11 N2 - HLA antigen status was assessed in non-related individuals and related family members with bird breeder's hypersensitivity pneumonitis (HP). 35% of 20 non-related patients carried HLABW40 compared to 10% of 861 normal controls (p less than 0.001, Pc less than 0.05, respectively). A consistent association of an HLA haplotype with disease was demonstrated in three of four families. Selected HLA antisera contained antibodies which blocked the blastogenic response to bird antigen. This study suggests the existence of an HLA associated Ir gene in bird breeder's HP. SN - 0077-0760 UR - https://www.unboundmedicine.com/medline/citation/876124/HLA_and_bird_breeder's_hypersensitivity_pneumonitis_ L2 - https://antibodies.cancer.gov/detail/CPTC-HLA-DPB1-2 DB - PRIME DP - Unbound Medicine ER -