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Hypokalemia in a pediatric intensive care unit.
Indian Pediatr 1996; 33(1):9-14IP

Abstract

OBJECTIVE

To examine the frequency, severity, risk factors and mortality of hypokalemia, and efficacy of therapy used for its correction.

DESIGN

Descriptive, retrospective analysis.

SAMPLE

290 patient records admitted consecutively to a Pediatric Intensive Care Unit (PICU) over a period of one year.

RESULTS

Forty three (14.8%) patients had 54 episodes of hypokalemia. Predisposing factors included the nature of primary disease (renal disease 19%, septicemia 19%, acute diarrhea 14%, heart disease with congestive failure, and meningoencephalitis 12% each), malnutrition (weight for age less than 80% in 72%) and therapy with drugs (diuretics, corticosteroids and antiasthma drugs). For correction of hpokalemia all the patients received 4-6 mEq potassium per 100 ml of intravenous fluids (slow correction). Seven patients (9 episodes), with ECG changes of hpokalemia, also received infusion of 0.3 mEq potassium/kg/hour till ECG became normal (rapid correction). Normal potassium level was achieved in all nine episodes where rapid correction was given, and in 40 of 45 episodes which received slow correction. The overall mortality among patients with hypokalemia (25.6%, 11/43) was significantly higher than that among the remaining PICU patients (10.9%, 27/247; odd's ratio 2.34; 95% confidence interval 1.3-4.2) (p < 0.05). All the patients receiving rapid correction survived.

CONCLUSIONS

Hypokalemia is a common problem among PICU patients. Early detection through regular monitoring and rapid correction may help in improving the outcome.

Authors+Show Affiliations

Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh.No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8772944

Citation

Singhi, S, and A Marudkar. "Hypokalemia in a Pediatric Intensive Care Unit." Indian Pediatrics, vol. 33, no. 1, 1996, pp. 9-14.
Singhi S, Marudkar A. Hypokalemia in a pediatric intensive care unit. Indian Pediatr. 1996;33(1):9-14.
Singhi, S., & Marudkar, A. (1996). Hypokalemia in a pediatric intensive care unit. Indian Pediatrics, 33(1), pp. 9-14.
Singhi S, Marudkar A. Hypokalemia in a Pediatric Intensive Care Unit. Indian Pediatr. 1996;33(1):9-14. PubMed PMID: 8772944.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Hypokalemia in a pediatric intensive care unit. AU - Singhi,S, AU - Marudkar,A, PY - 1996/1/1/pubmed PY - 1996/1/1/medline PY - 1996/1/1/entrez KW - Age Factors KW - Asia KW - Biology KW - Child KW - Demographic Factors KW - Developing Countries KW - Electrolyte Balance--changes KW - Hemic System KW - Homeostasis KW - Incidence KW - India KW - Measurement KW - Physiology KW - Population KW - Population Characteristics KW - Potassium Ion Level--changes KW - Research Methodology KW - Research Report KW - Risk Factors KW - Southern Asia KW - Treatment KW - Youth SP - 9 EP - 14 JF - Indian pediatrics JO - Indian Pediatr VL - 33 IS - 1 N2 - OBJECTIVE: To examine the frequency, severity, risk factors and mortality of hypokalemia, and efficacy of therapy used for its correction. DESIGN: Descriptive, retrospective analysis. SAMPLE: 290 patient records admitted consecutively to a Pediatric Intensive Care Unit (PICU) over a period of one year. RESULTS: Forty three (14.8%) patients had 54 episodes of hypokalemia. Predisposing factors included the nature of primary disease (renal disease 19%, septicemia 19%, acute diarrhea 14%, heart disease with congestive failure, and meningoencephalitis 12% each), malnutrition (weight for age less than 80% in 72%) and therapy with drugs (diuretics, corticosteroids and antiasthma drugs). For correction of hpokalemia all the patients received 4-6 mEq potassium per 100 ml of intravenous fluids (slow correction). Seven patients (9 episodes), with ECG changes of hpokalemia, also received infusion of 0.3 mEq potassium/kg/hour till ECG became normal (rapid correction). Normal potassium level was achieved in all nine episodes where rapid correction was given, and in 40 of 45 episodes which received slow correction. The overall mortality among patients with hypokalemia (25.6%, 11/43) was significantly higher than that among the remaining PICU patients (10.9%, 27/247; odd's ratio 2.34; 95% confidence interval 1.3-4.2) (p < 0.05). All the patients receiving rapid correction survived. CONCLUSIONS: Hypokalemia is a common problem among PICU patients. Early detection through regular monitoring and rapid correction may help in improving the outcome. SN - 0019-6061 UR - https://www.unboundmedicine.com/medline/citation/8772944/Hypokalemia_in_a_pediatric_intensive_care_unit_ L2 - http://www.diseaseinfosearch.org/result/3659 DB - PRIME DP - Unbound Medicine ER -