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Effect of pretreatment counseling on discontinuation rates in Chinese women given depo-medroxyprogesterone acetate for contraception.
Contraception. 1996 Jun; 53(6):357-61.C

Abstract

The study examined the effect of pretreatment counseling upon discontinuation of 150 mg depo-medroxyprogesterone acetate (Depo-Provera (DMPA)), given for contraception. A total of 421 Chinese women participated, 204 receiving detailed structured pretreatment and ongoing counseling on the hormonal effects and probable side effects of DMPA and 217 receiving only routine counseling. The primary study endpoint was termination rate; secondary endpoints were frequency of medical events and reasons for termination. Study termination rates were significantly lower in the intensive structured counseling group than in the routine counseling group. At one year, the total cumulative termination rates were 11% (23/204) and 42% (92/217), respectively (p < 0.0001). The most common reasons for terminating DMPA were menstrual changes. No pregnancy, serious or unexpected medical events were reported, nor were statistically or clinically significant changes in vital signs observed. We conclude that pretreatment counseling on expected side effects increases the acceptability of DMPA.

Authors+Show Affiliations

Sichuan Reproductive Health Institute, Chengdu, PR China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Controlled Clinical Trial
Journal Article
Multicenter Study

Language

eng

PubMed ID

8773423

Citation

Lei, Z W., et al. "Effect of Pretreatment Counseling On Discontinuation Rates in Chinese Women Given Depo-medroxyprogesterone Acetate for Contraception." Contraception, vol. 53, no. 6, 1996, pp. 357-61.
Lei ZW, Wu SC, Garceau RJ, et al. Effect of pretreatment counseling on discontinuation rates in Chinese women given depo-medroxyprogesterone acetate for contraception. Contraception. 1996;53(6):357-61.
Lei, Z. W., Wu, S. C., Garceau, R. J., Jiang, S., Yang, Q. Z., Wang, W. L., & Vander Meulen, T. C. (1996). Effect of pretreatment counseling on discontinuation rates in Chinese women given depo-medroxyprogesterone acetate for contraception. Contraception, 53(6), 357-61.
Lei ZW, et al. Effect of Pretreatment Counseling On Discontinuation Rates in Chinese Women Given Depo-medroxyprogesterone Acetate for Contraception. Contraception. 1996;53(6):357-61. PubMed PMID: 8773423.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of pretreatment counseling on discontinuation rates in Chinese women given depo-medroxyprogesterone acetate for contraception. AU - Lei,Z W, AU - Wu,S C, AU - Garceau,R J, AU - Jiang,S, AU - Yang,Q Z, AU - Wang,W L, AU - Vander Meulen,T C, PY - 1996/6/1/pubmed PY - 1996/6/1/medline PY - 1996/6/1/entrez KW - Asia KW - Breast Feeding KW - China KW - Clinic Activities KW - Comparative Studies KW - Contraception KW - Contraception Termination KW - Contraceptive Agents KW - Contraceptive Agents, Female KW - Contraceptive Agents, Progestin KW - Contraceptive Usage KW - Counseling KW - Depo-provera KW - Developing Countries KW - Diseases KW - Eastern Asia KW - Family Planning KW - Health KW - Infant Nutrition KW - Medroxyprogesterone Acetate KW - Menstruation Disorders KW - Method Acceptability KW - Nutrition KW - Organization And Administration KW - Program Activities KW - Programs KW - Research Methodology KW - Research Report KW - Studies SP - 357 EP - 61 JF - Contraception JO - Contraception VL - 53 IS - 6 N2 - The study examined the effect of pretreatment counseling upon discontinuation of 150 mg depo-medroxyprogesterone acetate (Depo-Provera (DMPA)), given for contraception. A total of 421 Chinese women participated, 204 receiving detailed structured pretreatment and ongoing counseling on the hormonal effects and probable side effects of DMPA and 217 receiving only routine counseling. The primary study endpoint was termination rate; secondary endpoints were frequency of medical events and reasons for termination. Study termination rates were significantly lower in the intensive structured counseling group than in the routine counseling group. At one year, the total cumulative termination rates were 11% (23/204) and 42% (92/217), respectively (p < 0.0001). The most common reasons for terminating DMPA were menstrual changes. No pregnancy, serious or unexpected medical events were reported, nor were statistically or clinically significant changes in vital signs observed. We conclude that pretreatment counseling on expected side effects increases the acceptability of DMPA. SN - 0010-7824 UR - https://www.unboundmedicine.com/medline/citation/8773423/Effect_of_pretreatment_counseling_on_discontinuation_rates_in_Chinese_women_given_depo_medroxyprogesterone_acetate_for_contraception_ L2 - https://linkinghub.elsevier.com/retrieve/pii/0010782496000856 DB - PRIME DP - Unbound Medicine ER -